Comparative effectiveness and safety of low-strength and high-strength direct oral anticoagulants compared with warfarin: a sequential cohort study

NL Pratt, E Ramsay, LMK Ellett, K Duszynski… - BMJ open, 2019 - bmjopen.bmj.com
Objectives The aim of this study was to compare effectiveness and safety of low-strength and
high-strength direct oral anticoagulants (DOACs) with warfarin in the Australian Veteran …

Comparison of the effectiveness and safety of direct oral anticoagulants: a nationwide propensity score–weighted study

AB Ingason, JP Hreinsson, AS Agustsson… - Blood …, 2023 - ashpublications.org
In the pivotal randomized controlled trials (RCTs) for patients with atrial fibrillation, direct oral
anticoagulants (DOACs) had similar or even superior efficacy and safety compared with …

Effectiveness and safety of direct oral anticoagulants in relation to temporal changes in their use

SR Lee, EK Choi, S Kwon, JH Jung… - … Quality and Outcomes, 2020 - Am Heart Assoc
Background: Since the direct oral anticoagulants (DOAC) were introduced, oral
anticoagulant (OAC) prescription patterns have rapidly changed in patients with atrial …

Safety of direct oral anticoagulants in real–world clinical practice: translating the trials to everyday clinical management

AM Fawzy, WY Yang, GYH Lip - Expert Opinion on Drug Safety, 2019 - Taylor & Francis
ABSTRACT Introduction: Direct oral anticoagulants (DOACs) may be regarded as some of
the most successful innovations in recent times. These drugs which were specifically …

Inappropriate doses of direct oral anticoagulants in real-world clinical practice: prevalence and associated factors. A subanalysis of the FANTASIIA Registry

M Ruiz Ortiz, J Muñiz, P Raña Míguez, I Roldán… - Ep …, 2018 - academic.oup.com
Aims To describe the prevalence and associated factors of inappropriate doses of direct oral
anticoagulants (DOAC) in a national registry of patients of real clinical practice. Methods and …

Risks and benefits of direct oral anticoagulants versus warfarin in a real world setting: cohort study in primary care

Y Vinogradova, C Coupland, T Hill, J Hippisley-Cox - bmj, 2018 - bmj.com
Objective To investigate the associations between direct oral anticoagulants (DOACs) and
risks of bleeding, ischaemic stroke, venous thromboembolism, and all cause mortality …

Oral anticoagulant dosing, administration, and storage: a cross-sectional survey of Canadian health care providers

S Piran, S Schulman, M Panju, M Pai - Journal of Thrombosis and …, 2018 - Springer
Direct oral anticoagulant (DOAC) use is increasing worldwide. However, if not taken or
prescribed correctly, DOACs have serious side effects. It is crucial that healthcare providers …

Major bleeding risk associated with oral anticoagulant in real clinical practice. A multicentre 3‐year period population‐based prospective cohort study

J Bouget, F Balusson, M Maignan… - British Journal of …, 2020 - Wiley Online Library
Aims The objective was to compare major bleeding risk of direct oral anticoagulants
(DOACs; per type and dose) with vitamin K antagonists (VKAs), irrespective of indication …

[HTML][HTML] Mortality outcomes in patients receiving direct oral anticoagulants: a systematic review and meta‐analysis of randomized controlled trials

C Chai‐Adisaksopha, C Hillis, T Isayama, W Lim… - Journal of Thrombosis …, 2015 - Elsevier
Summary Background Direct oral anticoagulants (DOACs) are widely used as an alternative
for warfarin. However, the impact of DOACs on mortality outcomes compared with warfarin …

Review of direct oral anticoagulants and guide for effective drug utilization

T Khachatryan, C Hauschild, J Hoff… - American Journal of …, 2019 - Springer
Direct oral anticoagulants (DOACs) have been developed as a viable and in some cases
superior alternative to warfarin. These agents have overcome some of the limitations of …