Tiny molecule, big power: multi-target approach for curcumin in diabetic cardiomyopathy

V Karuppagounder, S Arumugam, VV Giridharan… - Nutrition, 2017 - Elsevier
Diabetic cardiomyopathy (DCM) is described as impaired cardiac diastolic and systolic
functions. Diabetes mellitus (DM), a related cardiovascular disease, has become one of the …

Curcumin, a polyphenolic curcuminoid with its protective effects and molecular mechanisms in diabetes and diabetic cardiomyopathy

J Zheng, J Cheng, S Zheng, Q Feng… - Frontiers in …, 2018 - frontiersin.org
As the leading cause of morbidity and mortality in patients with diabetes, diabetic
cardiomyopathy (DCM) imposes enormous burden on individuals and public health …

[HTML][HTML] Curcumin and cardiovascular diseases: Focus on cellular targets and cascades

AM Pourbagher-Shahri, T Farkhondeh… - Biomedicine & …, 2021 - Elsevier
Cardiovascular diseases (CVDs) are one of the leading causes of the most considerable
mortality globally, and it has been tried to find the molecular mechanisms and design new …

Curcumin, the golden spice in treating cardiovascular diseases

H Li, A Sureda, HP Devkota, V Pittalà, D Barreca… - Biotechnology …, 2020 - Elsevier
Cardiovascular diseases (CVDs) cause the largest mortality worldwide, and much attention
has been focused to unravel the mechanisms and optimize the treatment regimens …

[HTML][HTML] Application of a novel curcumin analog in the management of diabetic cardiomyopathy

J Ren, JR Sowers - Diabetes, 2014 - ncbi.nlm.nih.gov
Diabetes mellitus is becoming an epidemic health threat and represents one of the most
prevalent chronic noncommunicable disorders. Cardiovascular complications are …

Experimental evidence for curcumin and its analogs for management of diabetes mellitus and its associated complications

S Rivera-Mancía, MC Lozada-García… - European Journal of …, 2015 - Elsevier
Diabetes mellitus is a serious world health problem and one of the most studied diseases; a
major concern about its treatment is that β-cell mass and functionality is hard to restore. In …

Curcumin alleviates diabetic cardiomyopathy in experimental diabetic rats

W Yu, J Wu, F Cai, J Xiang, W Zha, D Fan, S Guo… - PloS one, 2012 - journals.plos.org
Objectives Diabetic cardiomyopathy (DCM), characterized by myocardial structural and
functional changes, is an independent cardiomyopathy that develops in diabetic individuals …

Curcumin: a natural product for diabetes and its complications

S Fazel Nabavi, R Thiagarajan… - Current topics in …, 2015 - ingentaconnect.com
Curcumin is the yellow-colored bioactive constituent of the perennial plant, Curcuma longa
L., which possesses a wide range of physiological and pharmacological properties such as …

An update on molecular mechanisms of curcumin effect on diabetes

W Lu, F Khatibi Shahidi, K Khorsandi… - Journal of food …, 2022 - Wiley Online Library
Owing to its prevalent nature, diabetes mellitus has become one of the most serious
endocrine illnesses affecting a patient's quality of life due to the manifestation of side effects …

The effects of curcumin on diabetes mellitus: a systematic review

LT Marton, LM Pescinini-e-Salzedas… - Frontiers in …, 2021 - frontiersin.org
Diabetes mellitus (DM) is an ensemble of metabolic conditions that have reached pandemic
proportions worldwide. Pathology's multifactorial nature makes patient management …