Background While case reports and clinical trials reported withdrawal syndrome after
reduction and/or discontinuation of antidepressant drugs, no large study has been …

Introduction Evidence is lacking on withdrawal syndrome related to individual
antidepressants and relevant risk factors for severe reactions. Objective To ascertain …

Adaptation of the brain to the presence of a drug predicts withdrawal on cessation. The
outcome of adaptation is often referred to as 'physical dependence'in pharmacology, as …

OBJECTIVE: To study the drop-out rates in trials of selective serotonin and serotonin-
norepinephrine reuptake inhibitors (SSRIs and SNRIs). METHODS: This study is a …

Introduction The UK's current National Institute for Health and Care Excellence and the
American Psychiatric Association's depression guidelines state that withdrawal reactions …

Background Antidepressant discontinuation symptoms are becoming an increasingly
important part of clinical practice, but the incidence of antidepressant discontinuation …

Background Antidepressant withdrawal symptoms may mimic symptoms of depression
relapse and can be challenging for patients when tapering or discontinuing antidepressants …

Background Antidepressants are among the most commonly prescribed drugs worldwide.
They are often discontinued, frequently without the knowledge of the prescribing physician. It …

The SSRIs can be associated with withdrawal reactions and the objective of this study is to
test the existence of an association between reports of withdrawal syndromes with the …

We read with great interest the recent review of antidepressant withdrawal by Davies and
Read and the widespread press coverage which followed. We agree that symptoms …