The Gene-Environment Nexus: A Holistic Approach to Neurodegenerative Diseases
H Abdelzaher - Nutrigenomics and the Brain, 2022 - Springer
Neurodegenerative diseases affect millions of people globally and are characterized by their
poor prognosis and decreased quality of life. In the quest to shed light on the development …
poor prognosis and decreased quality of life. In the quest to shed light on the development …
Environmental Effect on Neuroinflammation and Neurodegeneration
Neurodegenerative disorders like Parkinson's disease and Alzheimer's disease, among
others, are characterized by the loss of a specific subset of neurons and glial activation …
others, are characterized by the loss of a specific subset of neurons and glial activation …
Environmental clues to brain disease
P Giannoni, F Bertaso, G Provensi - Frontiers in Aging Neuroscience, 2023 - frontiersin.org
Brain disease represents one of the major social and economic burden worldwide.
Identifying the factors impacting brain homeostasis, as well as the mechanisms involved in …
Identifying the factors impacting brain homeostasis, as well as the mechanisms involved in …
[HTML][HTML] Gene-by-environment interactions in Alzheimer's disease and Parkinson's disease
Diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD) arise from
complex interactions of genetic and environmental factors, with genetic variants regulating …
complex interactions of genetic and environmental factors, with genetic variants regulating …
Advances in understanding the pathogenetic mechanisms of neurodevelopmental disorders and neurodegenerative disease—The environment as a putative risk …
Neurodevelopmental disorders are generally influenced by not only genetic, but also
intrauterine and extrauterine factors that affect the fetal-maternal environment and/or brain …
intrauterine and extrauterine factors that affect the fetal-maternal environment and/or brain …
Genes and the environment in neurodegeneration
Neurodegenerative diseases are a heterogeneous group of pathologies which includes
complex multifactorial diseases, monogenic disorders and disorders for which inherited …
complex multifactorial diseases, monogenic disorders and disorders for which inherited …
Neuroinflammation represents a common theme amongst genetic and environmental risk factors for Alzheimer and Parkinson diseases
RJ Boyd, D Avramopoulos, LL Jantzie… - Journal of …, 2022 - Springer
Multifactorial diseases are characterized by inter-individual variation in etiology, age of
onset, and penetrance. These diseases tend to be relatively common and arise from the …
onset, and penetrance. These diseases tend to be relatively common and arise from the …
Genetics meets environment: evaluating gene–environment interactions in neurologic diseases
C Marras, SM Goldman - Seminars in neurology, 2011 - thieme-connect.com
The vast majority of disease is due to complex relationships between genetic and
environmental factors. Single genetic or environmental causes are rare. Unfortunately, this …
environmental factors. Single genetic or environmental causes are rare. Unfortunately, this …
Nature versus nurture: death of a dogma, and the road ahead
BJ Traynor, AB Singleton - Neuron, 2010 - cell.com
Interaction between the genome and the environment has been widely discussed in the
literature, but has the importance ascribed to understanding these interactions been …
literature, but has the importance ascribed to understanding these interactions been …
Role of early life exposure and environment on neurodegeneration: implications on brain disorders
Neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD),
Amyotrophic lateral sclerosis (ALS) and retinal degeneration have been studied extensively …
Amyotrophic lateral sclerosis (ALS) and retinal degeneration have been studied extensively …