[HTML][HTML] Insulin resistance in the defense against obesity
AR Saltiel - Cell metabolism, 2012 - cell.com
In the face of the current obesity epidemic, the nature of the relationship between
overnutrition and type 2 diabetes is of great importance. Obesity can be considered a state …
overnutrition and type 2 diabetes is of great importance. Obesity can be considered a state …
Mechanisms of obesity-associated insulin resistance: many choices on the menu
M Qatanani, MA Lazar - Genes & development, 2007 - genesdev.cshlp.org
Obesity-associated insulin resistance is a major risk factor for type 2 diabetes and
cardiovascular disease. In the past decade, a large number of endocrine, inflammatory …
cardiovascular disease. In the past decade, a large number of endocrine, inflammatory …
Selective insulin and leptin resistance in metabolic disorders
AC Könner, JC Brüning - Cell metabolism, 2012 - cell.com
Obesity represents a major risk factor for the development of insulin and leptin resistance,
ultimately leading to a pleiotropic spectrum of metabolic alterations. However, resistance to …
ultimately leading to a pleiotropic spectrum of metabolic alterations. However, resistance to …
Human obesity and insulin resistance: lessons from experiments of nature
S O'Rahilly - Fatty Acids and Lipotoxicity in Obesity and …, 2007 - Wiley Online Library
The past decade or so has seen the adipocyte catapulted from a position of relative
obscurity onto the centre stage of biomedical science. Having long been viewed largely as a …
obscurity onto the centre stage of biomedical science. Having long been viewed largely as a …
Obesity genes and insulin resistance
AC Belkina, GV Denis - Current Opinion in Endocrinology …, 2010 - journals.lww.com
Obesity genes and insulin resistance : Current Opinion in Endocrinology, Diabetes and
Obesity Obesity genes and insulin resistance : Current Opinion in Endocrinology, Diabetes …
Obesity Obesity genes and insulin resistance : Current Opinion in Endocrinology, Diabetes …
Insulin action and resistance in obesity and type 2 diabetes
MP Czech - Nature medicine, 2017 - nature.com
Nutritional excess is a major forerunner of type 2 diabetes. It enhances the secretion of
insulin, but attenuates insulin's metabolic actions in the liver, skeletal muscle and adipose …
insulin, but attenuates insulin's metabolic actions in the liver, skeletal muscle and adipose …
Molecular mechanisms involved in obesity-associated insulin resistance: therapeutical approach
S Fernández-Veledo, I Nieto-Vazquez… - … of physiology and …, 2009 - Taylor & Francis
Insulin resistance is an important contributor to the pathogenesis of T2D and obesity is a risk
factor for its development. It has been demonstrated that these obesity-related metabolic …
factor for its development. It has been demonstrated that these obesity-related metabolic …
Obesity, insulin resistance, and type 2 diabetes: associations and therapeutic implications
YT Wondmkun - Diabetes, Metabolic Syndrome and Obesity, 2020 - Taylor & Francis
Obesity is a triggering factor for diabetes associated with insulin resistance. In individuals
who are obese, higher amounts of non-esterified fatty acids, glycerol, hormones, and pro …
who are obese, higher amounts of non-esterified fatty acids, glycerol, hormones, and pro …
Leptin resistance in diet‐induced obesity: the role of hypothalamic inflammation
KCG De Git, RAH Adan - Obesity reviews, 2015 - Wiley Online Library
The consumption of W estern diets, high in sugar and saturated fat, is a crucial contributor to
the alarming incidence of obesity and its associated morbidities. These diets have been …
the alarming incidence of obesity and its associated morbidities. These diets have been …
[HTML][HTML] Implications of crosstalk between leptin and insulin signaling during the development of diet-induced obesity
CD Morrison, P Huypens, LK Stewart… - Biochimica et Biophysica …, 2009 - Elsevier
Insulin and leptin play complementary roles in regulating the consumption, uptake, oxidation
and storage of nutrients. Chronic consumption of diets that contain a high proportion of …
and storage of nutrients. Chronic consumption of diets that contain a high proportion of …