Long-range inhibitory intersection of a retrosplenial thalamocortical circuit by apical tuft-targeting CA1 neurons

N Yamawaki, X Li, L Lambot, LY Ren, J Radulovic… - Nature …, 2019 - nature.com
Hippocampus, granular retrosplenial cortex (RSCg), and anterior thalamic nuclei (ATN)
interact to mediate diverse cognitive functions. To identify cellular mechanisms underlying …

Optogenetic silencing of a corticotropin-releasing factor pathway from the central amygdala to the bed nucleus of the stria terminalis disrupts sustained fear

A Asok, A Draper, AF Hoffman, J Schulkin… - Molecular …, 2018 - nature.com
The lateral central nucleus of the amygdala (CeA L) and the dorsolateral bed nucleus of the
stria terminalis (BNST DL) coordinate the expression of shorter-and longer-lasting fears …

[HTML][HTML] Thalamus and claustrum control parallel layer 1 circuits in retrosplenial cortex

EKW Brennan, I Jedrasiak-Cape, S Kailasa, SP Rice… - Elife, 2021 - elifesciences.org
The granular retrosplenial cortex (RSG) is critical for both spatial and non-spatial behaviors,
but the underlying neural codes remain poorly understood. Here, we use optogenetic circuit …

Dynamic remodeling of a basolateral-to-central amygdala glutamatergic circuit across fear states

ND Hartley, AD Gaulden, R Báldi, ND Winters… - Nature …, 2019 - nature.com
Acquisition and extinction of learned fear responses utilize conserved but flexible neural
circuits. Here we show that acquisition of conditioned freezing behavior is associated with …

Evidence for two distinct thalamocortical circuits in retrosplenial cortex

E Lomi, ML Mathiasen, HY Cheng, N Zhang… - … of Learning and …, 2021 - Elsevier
Retrosplenial cortex (RSC) lies at the interface between sensory and cognitive networks in
the brain and mediates between these, although it is not yet known how. It has two distinct …

Dorsolateral septum somatostatin interneurons gate mobility to calibrate context-specific behavioral fear responses

A Besnard, Y Gao, M TaeWoo Kim, H Twarkowski… - Nature …, 2019 - nature.com
Adaptive fear responses to external threats rely upon efficient relay of computations
underlying contextual encoding to subcortical circuits. Brain-wide analysis of highly …

[HTML][HTML] Distinct dorsal and ventral hippocampal CA3 outputs govern contextual fear discrimination

A Besnard, SM Miller, A Sahay - Cell reports, 2020 - cell.com
Considerable work emphasizes a role for hippocampal circuits in governing contextual fear
discrimination. However, the intra-and extrahippocampal pathways that route contextual …

Serotonin receptor 2c-expressing cells in the ventral CA1 control attention via innervation of the Edinger–Westphal nucleus

X Li, W Chen, K Pan, H Li, P Pang, Y Guo, S Shu… - Nature …, 2018 - nature.com
The hippocampus is divided into dorsal and ventral zones along its principal axis. The
dorsal hippocampus is critical for learning and memory, yet the basic function of the ventral …

Synaptic targeting of double-projecting ventral CA1 hippocampal neurons to the medial prefrontal cortex and basal amygdala

WB Kim, JH Cho - Journal of Neuroscience, 2017 - Soc Neuroscience
The acquisition and retrieval of contextual fear memory requires coordinated neural activity
in the hippocampus, medial prefrontal cortex (mPFC), and amygdala. The contextual …

Bidirectional modulation of fear extinction by mediodorsal thalamic firing in mice

S Lee, T Ahmed, S Lee, H Kim, S Choi, DS Kim… - Nature …, 2012 - nature.com
The mediodorsal thalamic nucleus has been implicated in the control of memory processes.
However, the underlying neural mechanism remains unclear. Here we provide evidence for …