Innate lymphocytes in adipose tissue homeostasis and their alterations in obesity and colorectal cancer

M Del Cornò, L Conti, S Gessani - Frontiers in immunology, 2018 - frontiersin.org
Colorectal cancer (CRC) is the third most common cancer worldwide and a leading cause of
death, with burden expected to increase in the coming years. Enhanced adiposity …

Distinct blood and visceral adipose tissue regulatory T cell and innate lymphocyte profiles characterize obesity and colorectal cancer

G Donninelli, M Del Cornò, M Pierdominici… - Frontiers in …, 2017 - frontiersin.org
Visceral adipose tissue (VAT) is a main site where metabolic and immunologic processes
interplay to regulate, at local and systemic level, the inflammatory status and immune …

Adipose tissue immunity and cancer

V Catalán, J Gómez-Ambrosi, A Rodríguez… - Frontiers in …, 2013 - frontiersin.org
Inflammation and altered immune response are important components of obesity and
contribute greatly to the promotion of obesity-related metabolic complications, especially …

Obesity, cancer and the immune system: cross talks and complex interplay

HFM Kamel, HS Al-Amodi, S Abdelsattar - Handbook of Cancer and …, 2022 - Springer
Obesity and its accompanying comorbidities, including cancer, are rising worldwide. Obesity
is caused by a prolonged state of the high caloric consumption and the low energy …

Tissue immune cells fuel obesity-associated inflammation in adipose tissue and beyond

R Liu, BS Nikolajczyk - Frontiers in immunology, 2019 - frontiersin.org
Obesity-associated inflammation stems from a combination of cell-intrinsic changes of
individual immune cell subsets and the dynamic crosstalk amongst a broad array of immune …

Innate lymphoid cells as novel regulators of obesity and its‐associated metabolic dysfunction

D Yang, W Yang, Z Tian, JC van Velkinburgh… - obesity …, 2016 - Wiley Online Library
The increased prevalence of obesity worldwide has been accompanied by increases in risk
and rates of obesity‐associated metabolic dysfunctions, such as insulin resistance. The …

Role of innate lymphoid cells in obesity and metabolic disease

J Saetang, S Sangkhathat - Molecular medicine …, 2018 - spandidos-publications.com
The immune system has previously been demonstrated to be associated with the
pathophysiological development of metabolic abnormalities. However, the mechanisms …

[HTML][HTML] Visceral fat adipocytes from obese and colorectal cancer subjects exhibit distinct secretory and ω6 polyunsaturated fatty acid profiles and deliver …

M Del Cornò, M D'Archivio, L Conti, B Scazzocchio… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Obesity is a low-grade chronic inflammatory state representing an important risk factor for
colorectal cancer (CRC). Adipocytes strongly contribute to inflammation by producing …

Mechanisms linking obesity, inflammation and altered metabolism to colon carcinogenesis

E Yehuda‐Shnaidman, B Schwartz - obesity reviews, 2012 - Wiley Online Library
Due to its prevalence, obesity is now considered a global epidemic. It is linked to increased
risk of colorectal cancer, the third most common cancer and the second leading cause of …

Role of innate lymphoid cells in obesity and insulin resistance

H Chen, L Sun, L Feng, Y Yin, W Zhang - Frontiers in Endocrinology, 2022 - frontiersin.org
Obesity, a growing chronic metabolic disease, greatly increases the risk of metabolic
syndrome which includes type 2 diabetes, fatty liver and cardiovascular diseases. Obesity …