Aerosolized oxytocin increases cerebrospinal fluid oxytocin in rhesus macaques

ME Modi, F Connor-Stroud, R Landgraf… - …, 2014 - Elsevier
Intranasal (IN) administration is a widely used method for examining the effect of oxytocin
(OT) on social behavior and cognition in healthy subjects and psychiatric populations. IN-OT …

Similar effects of intranasal oxytocin administration and acute alcohol consumption on socio-cognitions, emotions and behaviour: Implications for the mechanisms of …

IJ Mitchell, SM Gillespie, A Abu-Akel - Neuroscience & Biobehavioral …, 2015 - Elsevier
Oxytocin (OT) plays a critical role in the formation of long lasting social attachments across a
range of mammalian species. Raising intracerebral OT levels by intranasal administration of …

In the nose or on the tongue? Contrasting motivational effects of oral and intranasal oxytocin on arousal and reward during social processing

J Kou, C Lan, Y Zhang, Q Wang, F Zhou, Z Zhao… - Translational …, 2021 - nature.com
Intranasal oxytocin exerts wide-ranging effects on socioemotional behavior and is proposed
as a potential therapeutic intervention in psychiatric disorders. However, following intranasal …

Oxytocin effects on the human brain: findings, questions, and future directions

O Weisman, R Feldman - Biological Psychiatry, 2013 - biologicalpsychiatryjournal.com
Since the discovery that intranasal administration of neuro-peptides can have a direct impact
on the human brain, extant research has been devoted to understanding the effects of …

Intranasal administration of oxytocin: behavioral and clinical effects, a review

JG Veening, B Olivier - Neuroscience & Biobehavioral Reviews, 2013 - Elsevier
The intranasal (IN-) administration of substances is attracting attention from scientists as well
as pharmaceutical companies. The effects are surprisingly fast and specific. The present …

[PDF][PDF] Intranasal oxytocin mechanisms can be better understood, but its effects on social cognition and behavior are not to be sniffed at

DS Quintana, JD Woolley - Biol Psychiatry, 2016 - academia.edu
The administration of intranasal oxytocin (IN-OT) has demonstrated a wide range of effects
on social behavior and cognition, which has led to its proposed use as a treatment for …

The role of intranasal oxytocin on social cognition: an integrative human lifespan approach

M Horta, D Pehlivanoglu, NC Ebner - Current behavioral neuroscience …, 2020 - Springer
Abstract Purpose of Review This narrative review synthesizes research from the last two
decades on the modulatory role of intranasal OT administration (IN-OT) on social cognition …

Sex differences in the neural and behavioral response to intranasal oxytocin and vasopressin during human social interaction

JK Rilling, AC DeMarco, PD Hackett, X Chen… - …, 2014 - Elsevier
Both oxytocin (OT) and vasopressin (AVP) are known to modulate social behavior, and
dysfunction in both systems has been postulated as a potential cause of certain psychiatric …

Intranasal oxytocin does not reduce age-related difficulties in social cognition

SA Grainger, JD Henry, HR Steinvik, EJ Vanman… - Hormones and …, 2018 - Elsevier
Oxytocin is a neuropeptide that plays a key role in social processing and there are several
studies suggesting that intranasally administered oxytocin may enhance social cognitive …

Evidence for intranasal oxytocin delivery to the brain: recent advances and future perspectives

DS Quintana, KT Smerud, OA Andreassen… - Therapeutic …, 2018 - Future Science
The neuropeptide oxytocin plays an evolutionarily conserved role in mammalian social
behavior. Despite striking effects on animal social behavior after intracerebroventricular drug …