Null results of oxytocin and vasopressin administration across a range of social cognitive and behavioral paradigms: Evidence from a randomized controlled trial

BA Tabak, AR Teed, E Castle, JM Dutcher… - …, 2019 - Elsevier
Research examining oxytocin and vasopressin in humans has the potential to elucidate
neurobiological mechanisms underlying human sociality that have been previously …

Acute and repeated intranasal oxytocin administration exerts anti-aggressive and pro-affiliative effects in male rats

F Calcagnoli, JC Kreutzmann, SF de Boer… - …, 2015 - Elsevier
Socio-emotional deficits and impulsive/aggressive outbursts are prevalent symptoms of
many neuropsychiatric disorders, and intranasal administration of oxytocin (OXT) is …

A direct examination of the effect of intranasal administration of oxytocin on approach-avoidance motor responses to emotional stimuli

A Theodoridou, IS Penton-Voak, AC Rowe - PloS one, 2013 - journals.plos.org
Oxytocin has been shown to promote a host of social behaviors in humans but the exact
mechanisms by which it exerts its effects are unspecified. One prominent theory suggests …

A randomized trial shows dose-frequency and genotype may determine the therapeutic efficacy of intranasal oxytocin

J Kou, Y Zhang, F Zhou, C Sindermann… - Psychological …, 2022 - cambridge.org
BackgroundThe neuropeptide oxytocin is proposed as a promising therapy for social
dysfunction by modulating amygdala-mediated social-emotional behavior. Although clinical …

Oxytocin delivered nasally or intraperitoneally reaches the brain and plasma of normal and oxytocin knockout mice

AS Smith, AC Korgan, WS Young - Pharmacological research, 2019 - Elsevier
Intranasal delivery of oxytocin (Oxt) has been identified as a potential therapeutic to target
human conditions characterized by social deficits, yet the ability of this administrative route …

Within vs. between-subject effects of intranasal oxytocin on the neural response to cooperative and non-cooperative social interactions

X Chen, P Gautam, E Haroon, JK Rilling - Psychoneuroendocrinology, 2017 - Elsevier
The neuropeptide oxytocin (OT) plays a critical role in modulating social behavior across a
wide range of vertebrate species. In humans, intranasal oxytocin (INOT) has been shown to …

Intranasal oxytocin increases covert attention to positive social cues

G Domes, M Sibold, L Schulze, A Lischke… - Psychological …, 2013 - cambridge.org
BackgroundThe neuropeptide oxytocin (OT) has positive effects on the processing of
emotional stimuli such as facial expressions. To date, research has focused primarily on …

The effect of intranasal administration of oxytocin on fear recognition

M Fischer-Shofty, SG Shamay-Tsoory, H Harari… - Neuropsychologia, 2010 - Elsevier
The oxytocinergic system has recently been placed amongst the most promising targets for
various psychiatric treatments due to its role in prosocial behavior and anxiety reduction …

The peptide that binds: a systematic review of oxytocin and its prosocial effects in humans

K MacDonald, TM MacDonald - Harvard review of psychiatry, 2010 - journals.lww.com
Oxytocin is a neuropeptide involved in a wide variety of social behaviors in diverse species.
Recent research on its effects in humans has generated an arresting picture of its role in the …

The acute effects of intranasal oxytocin administration on endocrine and sexual function in males

A Burri, M Heinrichs, M Schedlowski… - …, 2008 - Elsevier
The role of the neuropeptide oxytocin (OT) ranges from the modulation of neuroendocrine
physiological effects to the establishment of complex social and bonding behaviours …