Covering: 2000 to 2020 Natural products and their derivatives are commercially important
medicines, agrochemicals, flavors, fragrances, and food ingredients. Industrial strategies to …

Many biologically active natural products are produced by the host organisms using
dedicated biosynthetic pathways. The programming rules of these pathways may be …

Natural products and their related derivatives play a significant role in drug discovery and
have been the inspiration for the design of numerous synthetic bioactive compounds. With …

Microorganisms and plants synthesize a tremendous diversity of chemical compounds. For
centuries, these compounds have been used as medicines, foods and other useful …

Small molecules produced in Nature possess exquisite chemical diversity and continue to
be an inspiration for the development of new therapeutic agents. In their host organisms …

Metabolic engineers endeavor to create a bio-based manufacturing industry using microbes
to produce fuels, chemicals, and medicines. Plant natural products (PNPs) are historically …

Biosynthetic cascades represent a transformative technology that is revolutionizing the way
chemists approach synthetic challenges and have set new standards for what constitutes …

Natural products are a group of bioactive structurally diverse chemicals produced by
microorganisms and plants. These molecules and their derivatives have contributed to over …

The diversity and natural modularity of their biosynthetic pathways has turned natural
products into attractive, but challenging, targets for synthetic biology approaches. Here, we …

Organisms from all kingdoms of life produce a plethora of natural products that display a
range of biological activities. One key limitation of developing these natural products into …