Transcription termination and the control of the transcriptome: why, where and how to stop
O Porrua, D Libri - Nature reviews Molecular cell biology, 2015 - nature.com
Transcription termination occurs when the polymerase is released after a transcription event,
thus delimitating transcription units; however, the functional importance of termination …
thus delimitating transcription units; however, the functional importance of termination …
Transcription termination: variations on common themes
O Porrua, M Boudvillain, D Libri - Trends in Genetics, 2016 - cell.com
Transcription initiates pervasively in all organisms, which challenges the notion that the
information to be expressed is selected mainly based on mechanisms defining where and …
information to be expressed is selected mainly based on mechanisms defining where and …
Termination of transcription of short noncoding RNAs by RNA polymerase II
The RNA polymerase II transcription cycle is often divided into three major stages: initiation,
elongation, and termination. Research over the last decade has blurred these divisions and …
elongation, and termination. Research over the last decade has blurred these divisions and …
Mechanism of intrinsic transcription termination and antitermination
WS Yarnell, JW Roberts - Science, 1999 - science.org
Gene expression is modulated by regulatory elements that influence transcription elongation
by RNA polymerase: terminators that disrupt the elongation complex and release RNA, and …
by RNA polymerase: terminators that disrupt the elongation complex and release RNA, and …
Roadblock termination by reb1p restricts cryptic and readthrough transcription
J Colin, T Candelli, O Porrua, J Boulay, C Zhu… - Molecular cell, 2014 - cell.com
Widely transcribed compact genomes must cope with the major challenge of frequent
overlapping or concurrent transcription events. Efficient and timely transcription termination …
overlapping or concurrent transcription events. Efficient and timely transcription termination …
Knowing when to stop: Transcription termination on protein-coding genes by eukaryotic RNAPII
JB Rodríguez-Molina, S West, LA Passmore - Molecular cell, 2023 - cell.com
Gene expression is controlled in a dynamic and regulated manner to allow for the consistent
and steady expression of some proteins as well as the rapidly changing production of other …
and steady expression of some proteins as well as the rapidly changing production of other …
Connections between mRNA 3′ end processing and transcription termination
S Buratowski - Current opinion in cell biology, 2005 - Elsevier
Discoveries within the last few years have revealed that the multiple steps in gene
expression are remarkably integrated. There have recently been several advances in …
expression are remarkably integrated. There have recently been several advances in …
Termination of transcription by RNA polymerase II: BOOM!
JD Eaton, S West - Trends in Genetics, 2020 - cell.com
RNA polymerase II (Pol II) transcribes hundreds of thousands of transcription units–a
reaction always brought to a close by its termination. Because Pol II transcribes multiple …
reaction always brought to a close by its termination. Because Pol II transcribes multiple …
The transcription cycle in eukaryotes: from productive initiation to RNA polymerase II recycling
J Shandilya, SGE Roberts - Biochimica et Biophysica Acta (BBA)-Gene …, 2012 - Elsevier
The cycle of eukaryotic transcription, from initiation to elongation and termination is
regulated at multiple steps. Coordinated action of regulatory factors keeps in check the …
regulated at multiple steps. Coordinated action of regulatory factors keeps in check the …
Unravelling the means to an end: RNA polymerase II transcription termination
JN Kuehner, EL Pearson, C Moore - Nature reviews Molecular cell …, 2011 - nature.com
The pervasiveness of RNA synthesis in eukaryotes is largely the result of RNA polymerase II
(Pol II)-mediated transcription, and termination of its activity is necessary to partition the …
(Pol II)-mediated transcription, and termination of its activity is necessary to partition the …