The concept that different systems control episodic and surge secretion of gonadotropin‐
releasing hormone (GnRH) was well established by the time that GnRH was identified and …

This review recounts the origins and development of the concept of the hypothalamic
gonadotropin-releasing hormone (GnRH) pulse generator. It starts in the late 1960s when …

Increasing evidence accumulated during the past two decades has demonstrated that the
then-novel kisspeptin, which was discovered in 2001, the known neuropeptides neurokinin …

In the past decade since kisspeptin/neurokinin B/dynorphin (KNDy) cells were first identified
in the mammalian hypothalamus, a plethora of new research has emerged adding insights …

Gonadotropin hormone-releasing hormone (GnRH) is the key regulator of the reproductive
axis. Its pulsatile secretion determines the pattern of secretion of the gonadotropins follicle …

Gonadotropin-releasing hormone (GnRH) is the ultimate output signal of an intricate network
of neuroendocrine factors that, acting on the pituitary, trigger gonadotropin release. In turn …

Recently, a subset of neurons was identified in the arcuate nucleus of the hypothalamus that
colocalize three neuropeptides, kisspeptin, neurokinin B, and dynorphin, each of which has …

Acquisition of a mature pattern of gonadotropin-releasing hormone (GnRH) secretion from
the CNS is a hallmark of the pubertal process. Little is known about GnRH release during …

The reproductive neuropeptide gonadotropin-releasing hormone (GnRH) has two modes of
secretion. Besides the surge mode, which induces ovulation in females, the pulse mode of …

Gonadotropin-releasing hormone (GnRH) neurons in the basal forebrain are the final
common pathway through which the brain regulates reproduction. GnRH secretion occurs in …