Background Duchenne muscular dystrophy (DMD) is caused by DMD mutations leading to
dystrophin loss. Full‐length Dp427 is the primary dystrophin isoform expressed in muscle …

DUCHENNE muscular dystrophy is due to mutations in the dystrophin gene which is
predominantly expressed in muscle and brain. Since the disease is associated with …

Duchenne muscular dystrophy (DMD) is caused by a defect in a 427-kDa membrane-
associated protein: dystrophin. The DMD gene also encodes several shorter isoforms which …

The reading frame rule suggests that Duchenne muscular dystrophy (DMD) results from
DMD mutations causing an out-of-frame transcript, whereas the milder Becker muscular …

Brain function and its effect on motor performance in Duchenne muscular dystrophy (DMD)
is an emerging concept. The present study explored how cumulative dystrophin isoform loss …

Abstract Dystrophin Related Protein is the recently identified protein product of a large
autosomal transcript, showing significant similarity to dystrophin at the carboxyl terminus …

Duchenne muscular dystrophy is a multifactorial disease including a cognitive phenotype. It
is caused by mutations in the X-chromosomal DMD gene from which dystrophin is …

The absence of dystrophin in muscle fibers is associated with a major reduction in
dystrophin-associated proteins (DAPs) and disruption of the linkage between the …

Duchenne muscular dystrophy (DMD) is characterized by a defect in dystrophin, a high
molecular weight protein that is located predominantly in muscle, but which has been …

Mutations in the dystrophin gene lead to dystrophin deficiency, which is the cause of
Duchenne muscular dystrophy (DMD). This important discovery more than 10 years ago …