The past decade has been one of unprecedented discovery in psychiatry. Large-scale
genomic studies have identified hundreds of molecular risk factors and illuminated the …

The Psychiatric Genomics Consortium (PGC) is the largest consortium in the history of
psychiatry. This global effort is dedicated to rapid progress and open science, and in the …

The subjective and symptomatic basis of psychiatric diagnoses—coupled with high rates of
comorbidity, clinical heterogeneity, and the overwhelming complexity of the human brain …

The primary aim of precision medicine is to tailor healthcare more closely to the needs of
individual patients. This requires progress in two areas: the development of more precise …

Matt was in many ways the stereotypical “all-American” teenager: a multisport athlete, class
president, and valedictorian of his high school. It seemed preordained that he would attend …

The human genome project has spurred great enthusiasm in many research communities
and, of special interest to readers of Biological Psychiatry, has raised hope that genetic …

An edited volume that looks at the state of psychiatric genetics and how to chart a path
forward. In this edited collection, experts from psychiatric and statistical genetics …

Psychiatric genetics is in the midst of a profound transformation. For decades, the primary
challenge for the field was simply the reliable identification of risk genes. Now, for multiple …

Genome-wide association studies have identified hundreds of robust genetic associations
underlying psychiatric disorders and provided important biological insights into disease …

For over a century, psychiatric disorders have been defined by expert opinion and clinical
observation. The modern DSM has relied on a consensus of experts to define categorical …