Quantification of plasma EGFR mutations in patients with lung cancers: Comparison of the performance of ARMS-Plus and droplet digital PCR
L Wang, Q Guo, W Yu, L Qiao, M Zhao, C Zhang, X Hu… - Lung Cancer, 2017 - Elsevier
Objectives EGFR mutation is a key factor to predict EGFR-TKI efficacy. However, a
significant number of advanced patients do not have sufficient tumor specimens for …
significant number of advanced patients do not have sufficient tumor specimens for …
[HTML][HTML] Clinical validation of a highly sensitive assay to detect EGFR mutations in plasma cell-free DNA from patients with advanced lung adenocarcinoma
Y Li, H Xu, S Su, J Ye, J Chen, X Jin, Q Lin, D Zhang… - PLoS …, 2017 - journals.plos.org
Background Circulating tumor DNA (ctDNA) is a promising biomarker for noninvasive
epidermal growth factor receptor (EGFR) mutations detection in lung cancer patients, but the …
epidermal growth factor receptor (EGFR) mutations detection in lung cancer patients, but the …
[HTML][HTML] EGFR Mutations in Cell-free Plasma DNA from Patients with Advanced Lung Adenocarcinoma: Improved Detection by Droplet Digital PCR
A Buder, U Setinek, MJ Hochmair, S Schwab… - Targeted Oncology, 2019 - Springer
Background Analysis of cell-free DNA from blood could provide an alternative method for
identifying genomic changes in the tumors of patients with advanced lung adenocarcinoma …
identifying genomic changes in the tumors of patients with advanced lung adenocarcinoma …
Establishment and validation of a novel droplet digital PCR assay for ultrasensitive detection and dynamic monitoring of EGFR mutations in peripheral blood samples …
C Tang, L Zhu, L Zhang, C Tan, Z Peng, B Liu, W Liu… - Clinica Chimica …, 2020 - Elsevier
Abstract Background Droplet digital PCR (ddPCR)-based blood detection of EGFR
mutations plays significant roles in the individualized therapy of non-small-cell lung cancer …
mutations plays significant roles in the individualized therapy of non-small-cell lung cancer …
[HTML][HTML] A novel ARMS-based assay for the quantification of EGFR mutations in patients with lung adenocarcinoma
Y Zhu, Z Guo, Y Liu, X Zheng, G Yang… - Oncology …, 2018 - spandidos-publications.com
Quantification of epidermal growth factor receptor (EGFR) mutations is important for the
prediction of tyrosine kinase inhibitor (TKI) efficacy in patients with non‑small cell lung …
prediction of tyrosine kinase inhibitor (TKI) efficacy in patients with non‑small cell lung …
Use of SuperARMS EGFR mutation detection kit to detect EGFR in plasma cell-free DNA of patients with lung adenocarcinoma
S Cui, L Ye, H Wang, T Chu, Y Zhao, A Gu, L Xiong… - Clinical Lung Cancer, 2018 - Elsevier
Abstract Background The SuperARMS EGFR Mutation Detection Kit (SuperARMS) is highly
selective and sensitive and able to detect 41 of the most common somatic mutations in …
selective and sensitive and able to detect 41 of the most common somatic mutations in …
Comparison of five cell-free DNA isolation methods to detect the EGFR T790M mutation in plasma samples of patients with lung cancer
J Solassol, X Quantin, M Larrieux, R Senal… - Clinical Chemistry and …, 2018 - degruyter.com
Detection of EGFR mutations from circulating tumor DNA (ctDNA) has considerably modified
the medical care of non-small-cell lung cancer (NSCLC) patients, particularly of …
the medical care of non-small-cell lung cancer (NSCLC) patients, particularly of …
A comparative study of EGFR oncogenic mutations in matching tissue and plasma samples from patients with advanced non-small cell lung carcinoma
X Chai, P Ren, B Wei, J Ma, L Mai, DS Cram, Y Song… - Clinica Chimica …, 2016 - Elsevier
Background Plasma based EGFR mutation analysis is emerging as a viable alternative to
tumour tissue genotyping for patients with non-small cell lung carcinoma (NSCLC). The …
tumour tissue genotyping for patients with non-small cell lung carcinoma (NSCLC). The …
Digital PCR detection of EGFR somatic mutations in non-small-cell lung cancer formalin fixed paraffin embedded samples
TM Carvalho, RM Dourado, SM Nakatani… - Molecular and Cellular …, 2021 - Elsevier
Abstract Background Digital PCR (dPCR) is proposed to replace real time PCR and Sanger
sequencing for detection and quantification of rare mutations, frequently unnoticed in the …
sequencing for detection and quantification of rare mutations, frequently unnoticed in the …
[PDF][PDF] Comparison of EGFR mutation rates in lung adenocarcinoma tissue and pleural effusion samples
Y Guan, ZJ Wang, LQ Wang, DF Hua, J Liu - Genet Mol Res, 2016 - funpecrp.com.br
The goal of the current study was to investigate the differences in epidermal growth factor
receptor (EGFR) mutation rates in tumor tissue and pleural effusion specimens from patients …
receptor (EGFR) mutation rates in tumor tissue and pleural effusion specimens from patients …
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