The paradox of NKp46+ natural killer cells: drivers of severe hepatitis C virus-induced pathology but in-vivo resistance to interferon α treatment
Objective There is evidence that natural killer (NK) cells help control persistent viral
infections including hepatitis C virus (HCV). The phenotype and function of blood and …
infections including hepatitis C virus (HCV). The phenotype and function of blood and …
The natural killer cell response to HCV infection
G Ahlenstiel - Immune Network, 2013 - synapse.koreamed.org
In the last few years major progress has been made in better understanding the role of
natural killer (NK) cells in hepatitis C virus (HCV) infection. This includes multiple pathways …
natural killer (NK) cells in hepatitis C virus (HCV) infection. This includes multiple pathways …
Natural killer cells: multifaceted players with key roles in hepatitis C immunity
L Golden‐Mason, HR Rosen - Immunological reviews, 2013 - Wiley Online Library
Natural killer cells (NK s) are involved in every stage of hepatitis C viral (HCV) infection, from
protection against HCV acquisition and resolution in the acute phase to treatment‐induced …
protection against HCV acquisition and resolution in the acute phase to treatment‐induced …
A view to natural killer cells in hepatitis C
NH Shoukry, S Pelletier, KM Chang - Gastroenterology, 2011 - gastrojournal.org
Natural killer (NK) cells are among the earliest effector populations of the innate immune
response. They constitute 5%–15% of peripheral blood lymphocytes and 30%–50% of …
response. They constitute 5%–15% of peripheral blood lymphocytes and 30%–50% of …
[HTML][HTML] Natural killer cells in hepatitis C: Current progress
JC Yoon, CM Yang, Y Song, JM Lee - World journal of …, 2016 - ncbi.nlm.nih.gov
Patients infected with the hepatitis C virus (HCV) are characterized by a high incidence of
chronic infection, which results in chronic hepatitis, liver cirrhosis, and hepatocellular …
chronic infection, which results in chronic hepatitis, liver cirrhosis, and hepatocellular …
[PDF][PDF] Natural killer p46High expression defines a natural killer cell subset that is potentially involved in control of hepatitis C virus replication and modulation of liver …
B Krämer, C Körner, M Kebschull, A Glässner… - …, 2012 - Wiley Online Library
Natural killer (NK) cells play a role in the early control and natural course of hepatitis C virus
(HCV) infection. NK cell function is regulated by a multitude of receptors, including activating …
(HCV) infection. NK cell function is regulated by a multitude of receptors, including activating …
[HTML][HTML] Natural killer cells in viral hepatitis
B Rehermann - Cellular and molecular gastroenterology and …, 2015 - Elsevier
Natural killer (NK) cells are traditionally regarded as first-line effectors of the innate immune
response, but they also have a distinct role in chronic infection. Here, we review the role of …
response, but they also have a distinct role in chronic infection. Here, we review the role of …
[PDF][PDF] Increased natural killer cell cytotoxicity and NKp30 expression protects against hepatitis C virus infection in high‐risk individuals and inhibits replication in vitro
L Golden‐Mason, AL Cox, JA Randall, L Cheng… - …, 2010 - Wiley Online Library
CD56pos natural killer (NK)/natural T (NT) cells are important innate effectors providing the
first line of defense against viral infection. Enhanced NK activity has been shown to protect …
first line of defense against viral infection. Enhanced NK activity has been shown to protect …
Activation of natural killer cells during acute infection with hepatitis C virus
B Amadei, S Urbani, A Cazaly, P Fisicaro, A Zerbini… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: Natural killer (NK) cells are essential early after infection, not only
for viral containment but also for timely and efficient induction of adaptive responses. An …
for viral containment but also for timely and efficient induction of adaptive responses. An …
Chronic hepatitis C viral infection reduces NK cell frequency and suppresses cytokine secretion: Reversion by anti-viral treatment
O Dessouki, Y Kamiya, H Nagahama, M Tanaka… - Biochemical and …, 2010 - Elsevier
Impaired activity of NK (natural killer) cells has been proposed as a mechanism contributing
to viral persistence and chronic infection in hepatitis C (HCV) infection. We aimed to assess …
to viral persistence and chronic infection in hepatitis C (HCV) infection. We aimed to assess …