Proteomics reveals the potential protective mechanism of hydrogen sulfide on retinal ganglion cells in an ischemia/reperfusion injury animal model

H Liu, N Perumal, C Manicam, K Mercieca, V Prokosch - Pharmaceuticals, 2020 - mdpi.com
Glaucoma is the leading cause of irreversible blindness and is characterized by progressive
retinal ganglion cell (RGC) degeneration. Hydrogen sulfide (H2S) is a potent …

[HTML][HTML] Hydrogen sulfide protects retinal ganglion cells against glaucomatous injury in vitro and in vivo

H Liu, F Anders, S Thanos, C Mann… - … & visual science, 2017 - tvst.arvojournals.org
Purpose: Hydrogen sulfide (H 2 S) is recognized as a novel third signaling molecule and
gaseous neurotransmitter. Recently, cell protective properties within the central nervous and …

Hydrogen sulfide reduces ischemia and reperfusion injury in neuronal cells in a dose-and time-dependent manner

S Scheid, M Goeller, W Baar, J Wollborn… - International journal of …, 2021 - mdpi.com
Background: The ischemia-reperfusion injury (IRI) of neuronal tissue, such as the brain and
retina, leads to possible cell death and loss of function. Current treatment options are limited …

Relevant variations and neuroprotecive effect of hydrogen sulfide in a rat glaucoma model

S Huang, P Huang, X Liu, Z Lin, J Wang, S Xu, L Guo… - Neuroscience, 2017 - Elsevier
Glaucoma is an irreversible and blinding neurodegenerative disease of the eye, and is
characterized by progressive loss of retinal ganglion cells (RGCs). Since endogenous …

Inhalative as well as Intravenous Administration of H2S Provides Neuroprotection after Ischemia and Reperfusion Injury in the Rats' Retina

S Scheid, M Goeller, W Baar, J Wollborn… - International journal of …, 2022 - mdpi.com
Background: Neuronal ischemia-reperfusion injury (IRI), such as it can occur in glaucoma or
strokes, is associated with neuronal cell death and irreversible loss of function of the affected …

[HTML][HTML] Extracellular signal-regulated kinase 1/2 pathway is insufficiently involved in the neuroprotective effect by hydrogen sulfide supplement in experimental …

S Huang, P Huang, H Yu, Z Lin, X Liu… - … & Visual Science, 2019 - tvst.arvojournals.org
Purpose: Glaucoma is a neurodegenerative eye disease characterized by gradually
impaired visual field and irreversible blindness due to retinal ganglion cell (RGC) loss. Our …

Role of hydrogen sulfide in retinal diseases

J Du, H Jin, L Yang - Frontiers in Pharmacology, 2017 - frontiersin.org
As the third gasotransmitter, hydrogen sulfide (H2S) plays a crucial role in the physiology
and pathophysiology of many systems in the body, such as the nervous, cardiovascular …

Current perspective of hydrogen sulfide as a novel gaseous modulator of oxidative stress in glaucoma

Y Feng, V Prokosch, H Liu - Antioxidants, 2021 - mdpi.com
Glaucoma is a group of diseases characterized by the progressive loss of retinal ganglion
cells and their axons. Elevated intraocular pressure (IOP) is the main clinical manifestation …

Hydrogen sulfide supplement attenuates the apoptosis of retinal ganglion cells in experimental glaucoma

S Huang, P Huang, Z Lin, X Liu, X Xu, L Guo… - Experimental Eye …, 2018 - Elsevier
Glaucoma is a group of neurodegenerative eye diseases characterized by progressive
impairment of visual function due to loss of retinal ganglion cells (RGC). As hydrogen sulfide …

Hydrogen sulfide: novel endogenous and exogenous modulator of oxidative stress in retinal degeneration diseases

P Li, H Liu, X Shi, V Prokosch - Molecules, 2021 - mdpi.com
Oxidative stress (OS) damage can cause significant injury to cells, which is related to the
occurrence and development of many diseases. This pathological process is considered to …