Induction of surfactant protein A expression by cortisol facilitates prostaglandin synthesis in human chorionic trophoblasts

K Sun, D Brockman, B Campos… - The Journal of Clinical …, 2006 - academic.oup.com
Abstract Context: Surfactant protein A (SP-A) may be an important link between the
maturation of fetal organs and the initiation of parturition. However, the local expression of …

Surfactant Protein-A (SP-A) Selectively Inhibits Prostaglandin F (PGF) Production in Term Decidua: Implications for the Onset of Labor

VV Snegovskikh, V Bhandari, JR Wright… - The Journal of …, 2011 - academic.oup.com
Context: Labor is characterized by “decidual activation” with production of inflammatory
mediators. Recent data suggest that surfactant protein-A (SP-A) may be critical to the onset …

Secreted surfactant protein A from fetal membranes induces stress fibers in cultured human myometrial cells

M Breuiller-Fouché, O Dubois… - American Journal …, 2010 - journals.physiology.org
In the present study, we investigated the ability of human fetal membranes (amnion and
choriodecidua) to regulate human maternal uterine cell functions through the secretion of …

Surfactant protein‐A mRNA expression by human fetal membranes is increased in histological chorioamnionitis but not in spontaneous labour at term

YM Han, R Romero, YM Kim, JS Kim… - The Journal of …, 2007 - Wiley Online Library
Abstract Surfactant protein‐A (SP‐A) is produced by the fetal lung, participates in innate
immunity, and has been proposed to play a role in the initiation of parturition in mice …

Prostaglandins Regulate Surfactant Protein A (SP-A) Gene Expression in Human Fetal Lung in Vitro

MJ Acarregui, JM Snyder, MD Mitchell… - …, 1990 - academic.oup.com
We previously have observed that dexamethasone has a biphasic effect on surfactant
protein A (SP-A) mRNA levels in human fetal lung in vitro. At concentrations of 10-10-10-9 …

Surfactant protein A modulates the lipopolysaccharide-induced inflammatory response related to preterm birth

A Salminen, R Vuolteenaho, R Paananen, M Ojaniemi… - Cytokine, 2011 - Elsevier
Surfactant protein A (SP-A) functions in homeostasis of lung surfactant and in innate
immunity. SP-A is secreted by the fetal lung into amniotic fluid. Additionally it has been …

The concentration of surfactant protein-A in amniotic fluid decreases in spontaneous human parturition at term

T Chaiworapongsa, JS Hong, WM Hull… - The Journal of …, 2008 - Taylor & Francis
Objective. The fetus is thought to play a central role in the onset of labor. Pulmonary
surfactant protein (SP)-A, secreted by the maturing fetal lung, has been implicated in the …

New insights into the molecular endocrinology of parturition

CR Mendelson, JC Condon - The Journal of steroid biochemistry and …, 2005 - Elsevier
The signals that lead to the initiation of parturition have remained a mystery. We postulate
that in humans and other mammals, uterine quiescence is maintained by increased …

Lung surfactant proteins in the early human placenta

L Sati, Y Seval-Celik, R Demir - Histochemistry and cell biology, 2010 - Springer
Pulmonary surfactant is a complex mixture of phospholipids and four surfactant-associated
proteins (SP-A, SP-B, SP-C and SP-D). The biological functions of SP-A and SP-D are …

Adsorption of fetal surfactant protein SP-B on the human amnion at term and on amniocytes incubated with fetal surfactant in vitro

GE Newman, PJ Phizackerley, BA Lopez… - Reproduction …, 1991 - CSIRO Publishing
Fetal surfactant stimulates the synthesis of prostaglandins by slices of human amnion at term
and by a human amnion cell line, and these effects are partly dependent upon surfactant …