The eukaryote's mitochondrial network is perhaps the cell's most sophisticated and dynamic
responsive sensing system. Integrating metabolic, oxygen, or danger signals with inputs …

Mitochondria are often regarded as the powerhouse of the cell by generating the ultimate
energy transfer molecule, ATP, which is required for a multitude of cellular processes …

Mitochondria are perhaps the most sophisticated and dynamic responsive sensing systems
in eukaryotic cells. The role of mitochondria goes beyond their capacity to create molecular …

Cardiovascular disease is a major leading cause of morbidity and mortality in the United
States and elsewhere. Alterations in mitochondrial function are increasingly being …

In contrast to their role in cell types with higher energy demands, mitochondria in endothelial
cells primarily function in signaling cellular responses to environmental cues. This article …

Mitochondria are the source of cellular energy production and are present in different types
of cells. However, their function is especially important for the heart due to the high demands …

Mitochondria are highly dynamic organelles beyond powerhouses of a cell. These
components also play important roles in cell homeostasis by regulating cell function and …

Macrophages are pivotal in the initiation and development of atherosclerotic cardiovascular
diseases. Recent studies have reinforced the importance of mitochondria in metabolic and …

Vascular diseases, particularly atherosclerosis, are associated with high morbidity and
mortality. Endothelial cell (EC) or vascular smooth muscle cell (VSMC) dysfunction leads to …

Since the discovery that mitochondrial membrane permeabilization represents a critical step
in the regulation of intrinsic apoptosis, mitochondria have been viewed as pluripotent …