Eco-friendly synthesis, characterization, in-silico ADMET and molecular docking analysis of novel carbazole derivatives as antibacterial and antifungal agents
In search of novel biologically potent compounds, three novel organic molecules have been
synthesized. The structures of the prepared compounds have been characterized by …
synthesized. The structures of the prepared compounds have been characterized by …
Design and synthesis of new 4-methylthiazole derivatives: In vitro and in silico studies of antimicrobial activity
The development of resistance against antimicrobial drugs has become a world-wide issue.
It is predicted that some or perhaps all the antimicrobial drugs used in clinics will be out of …
It is predicted that some or perhaps all the antimicrobial drugs used in clinics will be out of …
Design, synthesis, characterization, in vitro screening, molecular docking, 3D-QSAR, and ADME-Tox investigations of novel pyrazole derivatives as antimicrobial …
M Chalkha, M Akhazzane, FZ Moussaid… - New Journal of …, 2022 - pubs.rsc.org
In this work, we report the synthesis of some new pyrazole derivatives via an efficient and
practical procedure. The structures of the obtained compounds were established using …
practical procedure. The structures of the obtained compounds were established using …
Synthesis, antimicrobial activity, and molecular modeling studies of some benzoxazole derivatives
MT Muhammed, G Kuyucuklu… - Letters in Drug …, 2022 - ingentaconnect.com
Background: The need to develop novel antimicrobial agents is apparent as infectious
diseases are increasing and resistance is rapidly developing against the drugs used in the …
diseases are increasing and resistance is rapidly developing against the drugs used in the …
Multicomponent synthesis, DFT calculations and molecular docking studies of novel thiazolyl-pyridazinones as potential antimicrobial agents against antibiotic …
S Abu-Melha, ZA Muhammad, AS Abouzid… - Journal of Molecular …, 2021 - Elsevier
Novel series of aryl (hetaryl) thiazolylpyridazinedione derivatives were synthesized via one-
pot three-component synthesis of maleic anhydride, thiosemicarbazide and the appropriate …
pot three-component synthesis of maleic anhydride, thiosemicarbazide and the appropriate …
Synthesis of new benzimidazole derivatives containing 1, 3, 4-thiadiazole: their in vitro antimicrobial, in silico molecular docking and molecular dynamic simulations …
ABSTRACT A series of some new benzimidazole-1, 3, 4-thiadiazoles was synthesized. The
structures of target substances were confirmed by using 1H-NMR and 13С-NMR …
structures of target substances were confirmed by using 1H-NMR and 13С-NMR …
New indazole–1, 2, 3–triazoles as potent antimicrobial agents: Design, synthesis, molecular modeling and in silico ADME profiles
SK Gandham, AA Kudale, TR Allaka, K Chepuri… - Journal of Molecular …, 2024 - Elsevier
Our current work is aimed at synthesizing novel derivatives of 1, 2, 3–triazolyl–indazoles,
applying docking techniques and biological evaluation in order to find active promising …
applying docking techniques and biological evaluation in order to find active promising …
Heterocyclic compounds bearing pyrimidine, oxazole and pyrazole moieties: design, computational, synthesis, characterization, antibacterial and molecular docking …
M Arshad - SN Applied Sciences, 2020 - Springer
The recent study represented, the computational analysis, synthesis, characterization,
antimicrobial and molecular docking assessment of three compounds with some important …
antimicrobial and molecular docking assessment of three compounds with some important …
Synthesis, SAR, in silico appraisal and anti-microbial study of substituted 2-aminobenzothiazoles derivatives
DG Anuse, SN Mali, BR Thorat… - … computer-aided drug …, 2020 - ingentaconnect.com
Background: Antimicrobial resistance is a major global health problem, which is being
rapidly deteriorating the quality of human health. Series of substituted N-(benzo [d] thiazol-2 …
rapidly deteriorating the quality of human health. Series of substituted N-(benzo [d] thiazol-2 …
Thiazole-pyrazoline hybrids as potential antimicrobial agent: Synthesis, biological evaluation, molecular docking, DFT studies and POM analysis
In this study, an efficient synthesis of new thiazole-pyrazoline hybrids was investigated and
hybrids were screened for their antimicrobial activities against four species of pathogenic …
hybrids were screened for their antimicrobial activities against four species of pathogenic …