Background In 2005, following several years of declining efficacy of chloroquine, the Ministry
of Health recommended the use of Amodiaquine/Artesunate combination therapy for the …

Abstract Background Artesunate-amodiaquine (AS+ AQ) and artemether-lumefantrine (AM-
L) are efficacious artemisinin combination therapy (ACT) regimens that have been widely …

The declining efficacy of chloroquine in the early 2000s in Ghana led to its replacement with
artesunate/amodiaquine (AS/AQ) combination as first-line drug for treating uncomplicated …

Background Combination therapy has become a new paradigm in malaria treatment.
Amodiaquine is a common partner drug in different malaria combination therapies used or …

We investigated the safety and efficacy of amodiaquine alone (AQ) and combined with
artesunate (AQ+ AS) in 308 Rwandan children 6–59 months old with uncomplicated …

Summary Background Many countries in Africa are considering a change to combination
treatment for falciparum malaria because of the increase in drug resistance. However, there …

Combining artesunate (AR) with existing antimalarial drugs may improve cure rates, delay
emergence of resistance and reduce parasite clearance time. In order to investigate the …

The aim of the present study was to compare different doses of chloroquine (CQ) and
amodiaquine (AQ) for the treatment of falciparum malaria in children. Children with …

Abstract Background Congo-Brazzaville adopted artemisinin-based combination therapy
(ACT) in 2006. Artesunate-amodiaquine (AS+ AQ) and artemether-lumefantrine are the first …

Background Increasing drug resistance limits the choice of efficacious chemotherapy
against Plasmodium falciparum malaria in Africa. Amodiaquine still retains efficacy against P …