Silica nanoparticle supported cationic lipids can effectively bind plasmidDNAs and transfect
mammalian cells with an efficiency that depends on both the particle size and lipid …

Cationic solid lipid nanoparticles (SLN) have recently been suggested for non-viral gene
delivery, as these particles consist of well tolerated substances, can bind DNA directly via …

Natural membrane vesicles, including extracellular vesicles and enveloped viruses,
participate in various events in vivo. To study and manipulate these events, biomembrane …

Our study investigated the manufacturing of lipid-based nanotherapeutics with stealth
properties for siRNA delivery by employing a diffusion-driven microfluidic process in one or …

Cationic lipid-and polymer-based nanodevices are considered appropriate alternatives for
virus-based particles for delivery of nucleic acids, including genes and siRNA, into …

The suitability of cationically modified solid-lipid nanoparticles (SLN) as a novel transfection
agent was investigated. SLN were produced by hot homogenisation using either Compritol …

Effective, reproducible, and scalable methods for DNA–lipid assembly are important for the
success of non-viral vectors in in vivo gene therapy. We hypothesized DNA–lipid assembly …

Solid lipid nanoparticles (SLNs) have been proposed in the 1990s as appropriate drug
delivery systems, and ever since they have been applied in a wide variety of cosmetic and …

The use of surface‐based methods for the delivery of therapeutics has recently generated
increasing interest. These platforms have tremendous potential to minimize detrimental side …

In this paper, the suitability of novel cationic solid-lipid nanoparticles (SLN) as a nonviral
transfection agent for gene delivery was investigated. SLN were produced by using the …