Summary Cytochrome P450 (P450) enzymes are of particular interest because of their
diversity of catalysis of reactions with xenobiotic substrates. The P450s are distributed …

Abstract Cytochrome P450 (P450) enzymes include a family of related enzymes that are
involved in metabolism of vitamins, steroids, fatty acids, and other chemicals. This review …

Abstract Cytochrome P-450 (P-450) enzymes have been studied extensively in experimental
animal models and such is known regarding their structures, regulation, and mechanisms of …

Many members of the superfamily of hemeproteins, known as cytochrome P450 (P450 or
CYP), are currently described in the literature (over 2000 at the date of this writing)[see …

Abstract Cytochrome P450 (P450) enzymes play dominant roles in the metabolism of toxic
chemicals, as well as drugs, steroids, and several other important groups of compounds …

The significance of cytochrome P450 catalyzed reactions has now been recognized for more
than 30 years [1] as one of nature's most common and sophisticated methods to oxidize …

Cytochromes P-450 are ubiquitous in nature. The levels of these hemoproteins can be
influenced by many chemicals and the enzymes in turn are capable of me-tabolizing many …

Cytochrome P450 (P450) enzymes play major roles in the metabolism of drugs,
carcinogens, steroids, eicosanoids, alkaloids, pesticides, and other important xenobiotics, as …

The cytochrome P450 (P450) enzymes are critically involved in the biosynthesis of sterols,
eicosanoids, and other physiologically important substances. The initial work on P450 …

The cytochrome P450 enzymes (P450s) catalyze a number of different reactions using a
basic chemical template. The course of events follows the order of substrate binding, 1 …