Oxidative stress, synaptic dysfunction, and Alzheimer's disease
E Tönnies, E Trushina - Journal of Alzheimer's Disease, 2017 - content.iospress.com
Alzheimer's disease (AD) is a devastating neurodegenerative disorder without a cure. Most
AD cases are sporadic where age represents the greatest risk factor. Lack of understanding …
AD cases are sporadic where age represents the greatest risk factor. Lack of understanding …
Roles of oxidative stress in synaptic dysfunction and neuronal cell death in Alzheimer's disease
G Plascencia-Villa, G Perry - Antioxidants, 2023 - mdpi.com
Alzheimer's disease (AD) is a brain disorder that progressively undermines memory and
thinking skills by affecting the hippocampus and entorhinal cortex. The main …
thinking skills by affecting the hippocampus and entorhinal cortex. The main …
Oxidative stress in neurodegenerative diseases: from molecular mechanisms to clinical applications
Z Liu, T Zhou, AC Ziegler, P Dimitrion… - Oxidative medicine and …, 2017 - Wiley Online Library
Increasing numbers of individuals, particularly the elderly, suffer from neurodegenerative
disorders. These diseases are normally characterized by progressive loss of neuron cells …
disorders. These diseases are normally characterized by progressive loss of neuron cells …
Causes of oxidative stress in Alzheimer disease
Oxidative stress is one of the earliest events of Alzheimer disease (AD), with implications as
an important mediator in the onset, progression and pathogenesis of the disease. The …
an important mediator in the onset, progression and pathogenesis of the disease. The …
Oxidative stress and the pathogenesis of Alzheimer′ s disease
Y Zhao, B Zhao - Oxidative medicine and cellular longevity, 2013 - Wiley Online Library
Alzheimer′ s disease (AD) is the most common neurodegenerative disease that causes
dementia in the elderly. Patients with AD suffer a gradual deterioration of memory and other …
dementia in the elderly. Patients with AD suffer a gradual deterioration of memory and other …
Mechanism of oxidative stress and synapse dysfunction in the pathogenesis of Alzheimer's disease: understanding the therapeutics strategies
Synapses are formed by interneuronal connections that permit a neuronal cell to pass an
electrical or chemical signal to another cell. This passage usually gets damaged or lost in …
electrical or chemical signal to another cell. This passage usually gets damaged or lost in …
Oxidative stress in Alzheimer's disease
Z Chen, C Zhong - Neuroscience bulletin, 2014 - Springer
Oxidative stress plays a significant role in the pathogenesis of Alzheimer's disease (AD), a
devastating disease of the elderly. The brain is more vulnerable than other organs to …
devastating disease of the elderly. The brain is more vulnerable than other organs to …
Alzheimer's disease: redox dysregulation as a common denominator for diverse pathogenic mechanisms
R Von Bernhardi, J Eugenín - Antioxidants & redox signaling, 2012 - liebertpub.com
Alzheimer's disease (AD) is the most common cause of dementia and a progressive
neurodegeneration that appears to result from multiple pathogenic mechanisms (including …
neurodegeneration that appears to result from multiple pathogenic mechanisms (including …
Interplay between mitochondrial oxidative disorders and proteostasis in Alzheimer's disease
E Llanos-González, ÁA Henares-Chavarino… - Frontiers in …, 2020 - frontiersin.org
Although the basis of Alzheimer's disease (AD) etiology remains unknown, oxidative stress
(OS) has been recognized as a prodromal factor associated to its progression. OS refers to …
(OS) has been recognized as a prodromal factor associated to its progression. OS refers to …
Oxidative stress in Alzheimer's disease: molecular hallmarks of underlying vulnerability
MS Uddin, MT Kabir - Biological, Diagnostic and Therapeutic Advances in …, 2019 - Springer
Alzheimer's disease (AD) is the most common neurodegenerative disease characterized by
the presence of senile plaques (SPs) and neurofibrillary tangles (NFTs) in the hippocampus …
the presence of senile plaques (SPs) and neurofibrillary tangles (NFTs) in the hippocampus …