Over the past decade, a subclassification of the molecular types of breast cancer has
evolved. This evolution has been driven partly by the limitations of the current classification …

Despite tremendous advances in breast cancer characterization and therapy over the last 20
years, clinicians still have difficulty accurately predicting the prognosis for individual breast …

Molecular portraits of breast cancer: tumour subtypes as distinct disease entities -
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Breast cancer is a complex disease encompassing multiple tumour entities each with a
characteristic morphology and behaviour. Current clinical practice relies on the recognition …

Epithelial breast malignancies are a group of several disease entities that vary in their
biology and response to specific therapies. Historically, classification of different molecular …

The initial steps into a better understanding of the heterogeneity and biology of breast
cancer were made at the onset of 2000, with the first identification of distinct molecular …

Breast carcinoma comprises a group of diseases with specific clinical, histopathologic and
molecular properties. Traditional classification use morphology to divide tumors into …

Traditionally, pathologic determinations of tumor size, lymph node status, endocrine receptor
status, and human epidermal growth factor receptor 2 (HER2) status have driven prognostic …

Breast cancer is a complex disease and different classifications, mostly based on clinical
and pathological features, have been used for guiding the management of patients. Most of …

Breast cancer is a heterogeneous disease, comprising multiple entities associated with
distinctive histological and biological features, clinical presentations and behaviours and …