LSF is a mammalian transcription factor that is rapidly and quantitatively phosphorylated
upon growth induction of resting, peripheral human T cells, as assayed by a reduction in its …

The mammalian transcription factor LSF (CP2/LBP-1c) binds cellular promoters modulated
by cell growth signals. We demonstrate here that LSF-DNA-binding activity is strikingly …

A limited number of transcription factors have been suggested to be regulated directly by
Erks within the Ras/mitogen-activated protein kinase signaling pathway. In this paper we …

Rlf is a ubiquitously expressed distinct relative of RalGDS that interacts with active Ras in
vitro. We now demonstrate that Rlf, when co‐expressed with Ras mutants, associates in vivo …

The ERF transcriptional repressor is a downstream effector of the RAS/ERK pathway that
interacts with and is directly phosphorylated by ERKs in vivo and in vitro. This …

Transcriptional regulation in mammalian cells is driven by a complex interplay of multiple
transcription factors that respond to signals from either external or internal stimuli. A single …

Transcription factor LSF is required for progression from quiescence through the cell cycle,
regulating thymidylate synthase (Tyms) expression at the G1/S boundary. Given the constant …

Cell cycle progression in mammalian cells from G1 into S phase requires sensing and
integration of multiple inputs, in order to determine whether to continue to cellular DNA …

The Elk-l and SRF transcription factors form a ternary complex at the c-fos serum response
element (SRE). Growth factor stimulation rapidly induces a reversible change in the …

Hepatocyte growth factor/scatter factor (HGF/SF) is the ligand of the MET tyrosine kinase
receptor. It is a pleiotropic mediator of epithelial cell proliferation, survival, motility, and …