Mammalian transcription factor LSF is a target of ERK signaling
Z Pagon, J Volker, GM Cooper… - Journal of cellular …, 2003 - Wiley Online Library
LSF is a mammalian transcription factor that is rapidly and quantitatively phosphorylated
upon growth induction of resting, peripheral human T cells, as assayed by a reduction in its …
upon growth induction of resting, peripheral human T cells, as assayed by a reduction in its …
Mitogenic stimulation of resting T cells causes rapid phosphorylation of the transcription factor LSF and increased DNA-binding activity.
JL Volker, LE Rameh, Q Zhu, J DeCaprio… - Genes & …, 1997 - genesdev.cshlp.org
The mammalian transcription factor LSF (CP2/LBP-1c) binds cellular promoters modulated
by cell growth signals. We demonstrate here that LSF-DNA-binding activity is strikingly …
by cell growth signals. We demonstrate here that LSF-DNA-binding activity is strikingly …
Transcriptional repressor ERF is a Ras/mitogen-activated protein kinase target that regulates cellular proliferation
L le Gallic, D Sgouras, G Beal Jr… - Molecular and cellular …, 1999 - Taylor & Francis
A limited number of transcription factors have been suggested to be regulated directly by
Erks within the Ras/mitogen-activated protein kinase signaling pathway. In this paper we …
Erks within the Ras/mitogen-activated protein kinase signaling pathway. In this paper we …
[HTML][HTML] Stimulation of gene induction and cell growth by the Ras effector Rlf
Rlf is a ubiquitously expressed distinct relative of RalGDS that interacts with active Ras in
vitro. We now demonstrate that Rlf, when co‐expressed with Ras mutants, associates in vivo …
vitro. We now demonstrate that Rlf, when co‐expressed with Ras mutants, associates in vivo …
The RAS-dependent ERF control of cell proliferation and differentiation is mediated by c-Myc repression
M Verykokakis, C Papadaki, E Vorgia… - Journal of Biological …, 2007 - ASBMB
The ERF transcriptional repressor is a downstream effector of the RAS/ERK pathway that
interacts with and is directly phosphorylated by ERKs in vivo and in vitro. This …
interacts with and is directly phosphorylated by ERKs in vivo and in vitro. This …
Lineage-specific and ubiquitous biological roles of the mammalian transcription factor LSF
J Veljkovic, U Hansen - Gene, 2004 - Elsevier
Transcriptional regulation in mammalian cells is driven by a complex interplay of multiple
transcription factors that respond to signals from either external or internal stimuli. A single …
transcription factors that respond to signals from either external or internal stimuli. A single …
Phosphorylation by Cyclin C/Cyclin-Dependent Kinase 2 following Mitogenic Stimulation of Murine Fibroblasts Inhibits Transcriptional Activity of LSF during G1 …
UH Saxena, CMH Powell, JK Fecko… - … and Cellular Biology, 2009 - Taylor & Francis
Transcription factor LSF is required for progression from quiescence through the cell cycle,
regulating thymidylate synthase (Tyms) expression at the G1/S boundary. Given the constant …
regulating thymidylate synthase (Tyms) expression at the G1/S boundary. Given the constant …
Transcription factors LSF and E2Fs: tandem cyclists driving G0 to S?
U Hansen, L Owens, U Saxena - Cell Cycle, 2009 - Taylor & Francis
Cell cycle progression in mammalian cells from G1 into S phase requires sensing and
integration of multiple inputs, in order to determine whether to continue to cellular DNA …
integration of multiple inputs, in order to determine whether to continue to cellular DNA …
The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain
R Marais, J Wynne, R Treisman - Cell, 1993 - cell.com
The Elk-l and SRF transcription factors form a ternary complex at the c-fos serum response
element (SRE). Growth factor stimulation rapidly induces a reversible change in the …
element (SRE). Growth factor stimulation rapidly induces a reversible change in the …
[PDF][PDF] Involvement of Ras-ERK signaling in multiple biological responses to HGF/SF
D Tulasne, R Paumelle, C Leroy… - ANNALS-NEW YORK …, 2002 - academia.edu
Hepatocyte growth factor/scatter factor (HGF/SF) is the ligand of the MET tyrosine kinase
receptor. It is a pleiotropic mediator of epithelial cell proliferation, survival, motility, and …
receptor. It is a pleiotropic mediator of epithelial cell proliferation, survival, motility, and …