Development of time-resolved spectroscopy system for quantitative noninvasive tissue measurement

M Miwa, Y Ueda, B Chance - Optical Tomography, Photon …, 1995 - spiedigitallibrary.org
Near IR time resolved spectroscopy has been studied for quantitative determination of
absorbance in highly scattering medium such as tissue. When a very narrow optical pulse is …

Quantitative absorption and scattering spectra in thick tissues using broadband diffuse optical spectroscopy

D Jakubowski, F Bevilacqua, S Merritt… - Biomedical Optical …, 2009 - books.google.com
Near-infrared spectroscopy is a well-established technique that has been applied to a
variety of medical diagnostic problems. Recent examples include detecting peripheral …

Time resolved reflectance and transmittance for the noninvasive measurement of tissue optical properties

MS Patterson, B Chance, BC Wilson - Applied optics, 1989 - opg.optica.org
When a picosecond light pulse is incident on biological tissue, the temporal characteristics
of the light backscattered from, or transmitted through, the sample carry information about …

Multiwavelength, wideband, intensity-modulated optical spectrometer for near-infrared spectroscopy and imaging

A Duncan, TL Whitlock, M Cope… - Photon Migration and …, 1993 - spiedigitallibrary.org
Quantitative determination of chromophore concentrations by near infrared spectroscopy
(NIRS) is possible by using the differential pathlength of the detected light, measured …

Simplified approach to characterize optical properties and blood oxygenation in tissue using continuous near-infrared light

H Liu, DA Boas, Y Zhang, AG Yodh… - … Photon Migration, and …, 1995 - spiedigitallibrary.org
We present a new data reduction algorithm to quantify absorption and reduced scattering
coefficients of living tissues. The method requires source-detector separations larger than 2 …

Absorption spectroscopy in tissue-simulating materials: a theoretical and experimental study of photon paths

MS Patterson, S Andersson-Engels, BC Wilson… - Applied …, 1995 - opg.optica.org
A diffusion model of noninvasive absorption spectroscopy was used to determine how the
change in signal resulting from a point absorber depends on the position of that absorber …

Experimental determination of photon propagation in highly absorbing and scattering media

J Ripoll, D Yessayan, G Zacharakis, V Ntziachristos - JOSA A, 2005 - opg.optica.org
Optical imaging and tomography in tissues can facilitate the quantitative study of several
important chromophores and fluorophores. Several theoretical models have been validated …

The potential of time-resolved reflectance measurements for the noninvasive determination of tissue optical properties

B Wilson, Y Park, Y Hefetz, M Patterson… - Thermal and Optical …, 1989 - spiedigitallibrary.org
The time spectrum of photons diffusely reflected from a turbid medium such as tissue
following a short incident light pulse depends on the optical absorption and scattering …

Measuring absorption coefficients in small volumes of highly scattering media: source-detector separations for which path lengths do not depend on scattering …

JR Mourant, IJ Bigio, DA Jack, TM Johnson… - Applied optics, 1997 - opg.optica.org
The noninvasive measurement of variations in absorption that are due to changes in
concentrations of biochemically relevant compounds in tissue is important in many clinical …

Detection and localization of absorbers in scattering media using frequency-domain principles

KW Berndt, JR Lakowicz - Time-Resolved Spectroscopy and …, 1991 - spiedigitallibrary.org
We report on time-resolved reflectance imaging experiments on a scattering medium
containing a spatially limited absorber. The medium is illuminated at two positions with …