Abstract C-kit receptor (CD117) and its ligand, stem cell factor, play a key role in normal
hematopoiesis. It has been demonstrated that its expression extremely increases in …

BACKGROUND AND OBJECTIVE: The receptor for stem cell factor (CD117) is the gene
product of the c-kit proto-ontogene. Together with its ligand, the stem cell factor (SCF), it …

The c-kit proto-oncogene encodes a 145 kd tyrosyne kinase transmembrane receptor, which
plays a key role in haemopoiesis. The c-kit has been classified as CD117 and is especially …

CD117 is a transmembrane protein receptor encoded by the c-kit protooncogene. The
CD117 ligand is stem cell factor, an important hematopoietic regulator. CD117 is present on …

Context.—Flow cytometric immunophenotyping is a useful ancillary tool in the diagnosis and
subclassification of acute myeloid leukemias (AMLs). A recent study concluded that CD64 is …

BACKGROUND AND OBJECTIVE: The CD117 molecule is an antigen more frequently
found on early normal and leukemic hematopoietic cells, but its correlation with the FAB …

Investigating 208 patients with acute haematological malignancies, we found that stem cell
factor receptor (SCFR) was expressed on high numbers of blast cells from the vast majority …

We assessed the diagnostic usefulness of adding anti-CD117 to our existing flow cytometric
profile in the analysis of 150 consecutive cases of acute leukemia (de novo or relapsed …

The prognostic significance of selected markers of leukemic cells is well known. CD7 and
CD56 expression at diagnosis has been associated with low remission rates and biological …

Background: Acute myeloid leukemia (AML) is a highly heterogeneous disease
accompanied by the arrest of myeloid cell lineage differentiation due to accumulation of …