Cervicovaginal immune activation in Zambian women with female genital schistosomiasis

AS Sturt, EL Webb, C Patterson, CR Phiri… - Frontiers in …, 2021 - frontiersin.org
HIV-1 infection disproportionately affects women in sub-Saharan Africa, where areas of high
HIV-1 prevalence and Schistosoma haematobium endemicity largely overlap. Female …

[HTML][HTML] Beyond the barrier: female genital schistosomiasis as a potential risk factor for HIV-1 acquisition

AS Sturt, EL Webb, SC Francis, RJ Hayes… - Acta tropica, 2020 - Elsevier
Female genital schistosomiasis (FGS) results from egg-deposition in the female reproductive
tract primarily by the waterborne parasite Schistosoma (S.) haematobium, and less …

Altered cervical mucosal gene expression and lower interleukin 15 levels in women with Schistosoma haematobium infection but not in women with Schistosoma …

KM Dupnik, MH Lee, P Mishra, MJ Reust… - The Journal of …, 2019 - academic.oup.com
Background Schistosomiasis increases the risk of human immunodeficiency virus (HIV)
acquisition in women by mechanisms that are incompletely defined. Our objective was to …

Association of female genital schistosomiasis with the cervicovaginal microbiota and sexually transmitted infections in Zambian women

AS Sturt, EL Webb, L Himschoot… - Open Forum …, 2021 - academic.oup.com
Background The cervicovaginal microbiota, including sexually transmitted infections (STIs),
have not been well described in female genital schistosomiasis (FGS). Methods Women …

Schistosoma mansoni infection and socio-behavioural predictors of HIV risk: a cross-sectional study in women from Uganda

S Yegorov, RM Galiwango, SV Good, J Mpendo… - BMC infectious …, 2018 - Springer
Background Schistosoma mansoni infection has been associated with increased risk of HIV
transmission in African women. This association might be causal or mediated through …

Female genital Schistosomiasis and HIV-1 incidence in Zambian women: a retrospective cohort study

AS Sturt, EL Webb, CR Phiri, M Mudenda… - Open Forum …, 2021 - academic.oup.com
Background Female genital schistosomiasis (FGS) has been associated with prevalent HIV-
1. We estimated the incidence of HIV-1 infection in Zambian women with and without FGS …

Effect of Female Genital Schistosomiasis and Anti-Schistosomal Treatment on Monocytes, CD4+ T-Cells and CCR5 Expression in the Female Genital Tract

E Kleppa, V Ramsuran, S Zulu, GH Karlsen, A Bere… - PloS one, 2014 - journals.plos.org
Background Schistosoma haematobium is a waterborne parasite that may cause female
genital schistosomiasis (FGS), characterized by genital mucosal lesions. There is clinical …

[HTML][HTML] Schistosoma mansoni treatment reduces HIV entry into cervical CD4+ T cells and induces IFN-I pathways

S Yegorov, V Joag, RM Galiwango, SV Good… - Nature …, 2019 - nature.com
Schistosoma mansoni (Sm) infection has been linked with an increased risk of HIV
acquisition in women. Therefore, defining the mechanism (s) by which Sm alters HIV …

Female genital schistosomiasis and HIV: research urgently needed to improve understanding of the health impacts of this important coinfection

DP O'Brien, N Ford, AG Djirmay, A Calmy… - JAIDS Journal of …, 2019 - journals.lww.com
Evidence suggests that there are important interactions between HIV and female genital
schistosomiasis (FGS) that may have significant effects on individual and population health …

Schistosoma haematobium Infection and CD4+ T-Cell Levels: A Cross-Sectional Study of Young South African Women

E Kleppa, KF Klinge, HN Galaphaththi-Arachchige… - PLoS …, 2015 - journals.plos.org
Schistosoma (S.) haematobium causes urogenital schistosomiasis and has been
hypothesized to adversely impact HIV transmission and progression. On the other hand it …