Nanoparticles of resveratrol attenuates oxidative stress and inflammation after ischemic stroke in rats

M Ashafaq, MI Alam, A Khan, F Islam… - International …, 2021 - Elsevier
Resveratrol is a nutraceutical compound that has exciting pharmacological potential in
different diseases, including stroke. Due to its low bioavailability, the efficacy of resveratrol is …

[HTML][HTML] Resveratrol alleviates nerve injury after cerebral ischemia and reperfusion in mice by inhibiting inflammation and apoptosis

L Fang, H Gao, W Zhang, W Zhang… - International Journal of …, 2015 - ncbi.nlm.nih.gov
The role of resveratrol in cerebral ischemia/reperfusion injury is not well understood. The
aim of this study was to investigate whether resveratrol modulates inflammation and …

Resveratrol exerts its neuroprotective effect by modulating mitochondrial dysfunctions and associated cell death during cerebral ischemia

S Yousuf, F Atif, M Ahmad, N Hoda, T Ishrat, B Khan… - Brain research, 2009 - Elsevier
Free radicals are known to cause secondary neuronal damage in cerebral
ischemia/reperfusion (I/R). We investigated here the neuroprotective effect of resveratrol, a …

Resveratrol has an overall neuroprotective role in ischemic stroke: a meta-analysis in rodents

J Liu, J He, Y Huang, Z Hu - Frontiers in Pharmacology, 2021 - frontiersin.org
Background: Resveratrol, a natural polyphenolic phytoalexin, is broadly presented in dietary
sources. Previous research has suggested its potential neuroprotective effects on ischemic …

Cerebroprotective potential of resveratrol through anti-oxidant and anti-inflammatory mechanisms in rats

P Orsu, B Murthy, A Akula - Journal of Neural Transmission, 2013 - Springer
Oxidative stress and inflammation are two important pathological mechanisms involved in
cerebral ischemia and reperfusion injury. In pathological conditions such as cerebral …

A comprehensive review on the neuroprotective potential of resveratrol in ischemic stroke

M Owjfard, Z Rahimian, F Karimi, A Borhani-Haghighi… - Heliyon, 2024 - cell.com
Stroke is the second leading cause of death and the third leading cause of disability
worldwide. Globally, 68% of all strokes are ischemic, with 32% being hemorrhagic. Ischemic …

Therapeutic effects of resveratrol on ischemia–reperfusion injury in the nervous system

A Sarkaki, M Rashidi, M Ranjbaran… - Neurochemical …, 2021 - Springer
Resveratrol is a phenol compound produced by some plants in response to pathogens,
infection, or physical injury. It is well-known that resveratrol has antioxidant and protective …

A meta-analysis of resveratrol protects against cerebral ischemia/reperfusion injury: Evidence from rats studies and insight into molecular mechanisms

R Xue, S Gao, Y Zhang, X Cui, W Mo, J Xu… - Frontiers in …, 2022 - frontiersin.org
Objective: To evaluate the neuroprotective effect of resveratrol (RES) in rat models of
cerebral ischemia/reperfusion (I/R) injury. Data sources: PubMed, Embase, MEDLINE …

Protective effect of resveratrol against oxidative stress in middle cerebral artery occlusion model of stroke in rats

K Sinha, G Chaudhary, YK Gupta - Life sciences, 2002 - Elsevier
Free radicals have been implicated in neuronal injury during ischemia reperfusion in stroke.
Trans resveratrol, a potent antioxidant, polyphenolic compound found in grapes and wines …

Resveratrol delivery by albumin nanoparticles improved neurological function and neuronal damage in transient middle cerebral artery occlusion rats

H Xu, Y Hua, J Zhong, X Li, W Xu, Y Cai… - Frontiers in …, 2018 - frontiersin.org
Human serum albumin (HSA) is an intrinsic protein and important carrier that transports
endogenous as well as exogenous substances. It is demonstrated in this study that the …