Whole exome sequencing identifies putative predictors of recurrent prostate cancer with high accuracy

J Liu, R Mao, G Ren, X Liu, Y Zhang… - OMICS: A Journal of …, 2019 - liebertpub.com
Prostate cancer (PCa) is a highly common cancer among men but lacks robust diagnostics
that can predict disease recurrence after initial treatment, for example, with radical …

[HTML][HTML] A novel stratification framework for predicting outcome in patients with prostate cancer

BA Luca, V Moulton, C Ellis, DR Edwards… - British journal of …, 2020 - nature.com
Background Unsupervised learning methods, such as Hierarchical Cluster Analysis, are
commonly used for the analysis of genomic platform data. Unfortunately, such approaches …

Optimizing molecular signatures for predicting prostate cancer recurrence

Y Sun, S Goodison - The Prostate, 2009 - Wiley Online Library
BACKGROUND The derivation of molecular signatures indicative of disease status and
predictive of subsequent behavior could facilitate the optimal choice of treatment for prostate …

Gene networks and microRNAs implicated in aggressive prostate cancer

L Wang, H Tang, V Thayanithy, S Subramanian… - Cancer research, 2009 - AACR
Prostate cancer, a complex disease, can be relatively harmless or extremely aggressive. To
identify candidate genes involved in causal pathways of aggressive prostate cancer, we …

[HTML][HTML] Gene expression relationship between prostate cancer cells of Gleason 3, 4 and normal epithelial cells as revealed by cell type-specific transcriptomes

LE Pascal, RZN Vêncio, LS Page, ES Liebeskind… - BMC cancer, 2009 - Springer
Background Prostate cancer cells in primary tumors have been typed CD10-/CD13-/CD24
hi/CD26+/CD38 lo/CD44-/CD104-. This CD phenotype suggests a lineage relationship …

Expression of cell cycle‐regulated genes and prostate cancer prognosis in a population‐based cohort

R Rubicz, S Zhao, C April, JL Wright, S Kolb… - The …, 2015 - Wiley Online Library
BACKGROUND Prostate cancer (PCa) is clinically and biologically heterogeneous, making
it difficult to predict at detection whether it will take an indolent or aggressive disease course …

[HTML][HTML] A four gene signature predictive of recurrent prostate cancer

J Komisarof, M McCall, L Newman, W Bshara… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Prostate cancer is the most common form of non-dermatological cancer among US men,
with an increasing incidence due to the aging population. Patients diagnosed with clinically …

[HTML][HTML] The Development of a Gleason Score-Related Gene Signature for Predicting the Prognosis of Prostate Cancer

Y Yimamu, X Yang, J Chen, C Luo, W Xiao… - Journal of Clinical …, 2022 - mdpi.com
The recurrence of prostate cancer (PCa) is intrinsically linked to increased mortality. The
goal of this study was to develop an efficient and reliable prognosis prediction signature for …

[HTML][HTML] Development, Validation, and Clinical Utility of a Six-gene Signature to Predict Aggressive Prostate Cancer

A Krzyzanowska, S Barron, DF Higgins… - European Urology …, 2023 - Elsevier
Background Molecular signatures in prostate cancer (PCa) tissue can provide useful
prognostic information to improve the understanding of a patient's risk of harbouring …

Principal component analysis of RNA-seq data unveils a novel prostate cancer-associated gene expression signature

Y Perera, A Gonzalez, R Perez - bioRxiv, 2020 - biorxiv.org
Prostate cancer is a highly heterogeneous disease and the second more common tumor in
males. Molecular and genetic profiles are currently used to identify subtypes and to guide …