Molecular genetic profiling of gleason grades 3 and 4/5 prostate cancer

M Shekar, Z Zhang, M Caldwell, Z Chen… - US Patent App. 10 …, 2005 - Google Patents
Many genes are affected in proState cancers which have not been previously identified. This
includes genes that have been up-regulated or down-regulated. Monitoring the expression …

[HTML][HTML] Retrospective study testing next generation sequencing of selected cancer-associated genes in resected prostate cancer

ML Iacono, C Buttigliero, V Monica, E Bollito… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Retrospective study testing next generation sequencing of selected cancer-associated genes in
resected prostate cancer - PMC Back to Top Skip to main content NIH NLM Logo Access keys …

Transcriptomic heterogeneity of expansile cribriform and other Gleason Pattern 4 prostate cancer subtypes

MR Chappidi, M Sjöström, NY Greenland… - European Urology …, 2024 - Elsevier
Background Prostate cancers featuring an expansile cribriform (EC) pattern are associated
with worse clinical outcomes following radical prostatectomy (RP). However, studies of the …

[HTML][HTML] Artificial intelligence unravels interpretable malignancy grades of prostate cancer on histology images

O Eminaga, F Saad, Z Tian, U Wolffgang… - npj Imaging, 2024 - nature.com
Malignancy grading of prostate cancer (PCa) is fundamental for risk stratification, patient
counseling, and treatment decision-making. Deep learning has shown potential to improve …

[HTML][HTML] A 10‑gene signature as a predictor of biochemical recurrence after radical prostatectomy in patients with prostate cancer and a Gleason score≥ 7

X Wu, D Lv, M Lei, C Cai, Z Zhao… - Oncology …, 2020 - spandidos-publications.com
The time and speed of biochemical recurrence (BCR) of prostate cancer (PCa) after radical
prostatectomy (RP) is highly variable. Stratification methods based on TNM staging and …

Use of expression analysis to predict outcome after radical prostatectomy

PG Febbo, WR Sellers - The Journal of urology, 2003 - Elsevier
PURPOSE: We summarize and discuss our recent work exploring the use of gene
expression analysis for the prediction of histopathological features of prostate cancer and …

Clinical-genomic characterization unveils more aggressive disease features in elderly prostate cancer patients with low-grade disease

H Goldberg, D Spratt, T Chandrasekar… - European Urology …, 2021 - Elsevier
Background Over 20% of men diagnosed with prostate cancer (PC) are≥ 75 yr old. More
objective disease-specific indices for predicting outcomes beyond chronological age are …

Molecular markers to identify patients at risk for recurrence after primary treatment for prostate cancer

C Kumar-Sinha, AM Chinnaiyan - Urology, 2003 - Elsevier
Accurate prognostication is a prerequisite for accurate therapeutics and management of
prostate cancer because indolent tumors may require no intervention, whereas aggressive …

IPPC: an interactive platform for prostate cancer multi-omics data integration and analysis

X Ye, F Peng, J Liu, H Zhao, W Chen… - Journal of Molecular …, 2021 - academic.oup.com
Prostate cancer is a clinically heterogeneous disease and remains the most common non-
skin malignancy in men worldwide (Abate-Shen and Shen, 2000; Litwin and Tan, 2017) …

[HTML][HTML] Identification of a candidate prognostic gene signature by transcriptome analysis of matched pre-and post-treatment prostatic biopsies from patients with …

P Rajan, J Stockley, IM Sudbery, JT Fleming, A Hedley… - BMC cancer, 2014 - Springer
Background Although chemotherapy for prostate cancer (PCa) can improve patient survival,
some tumours are chemo-resistant. Tumour molecular profiles may help identify the …