Efficient and site-specific radiolabeling reactions are essential in molecular probe synthesis.
Thus, selecting an effective method for radiolabeling that does not affect bioactivity of the …

From the X-ray crystal structures of Ga–DOTA chelates, we were able to deduce that two free
carboxylate groups of the radiogallium–DOTA complex may be utilized for coupling to …

The DATA chelators are a novel class of tri‐anionic ligands based on 6‐amino‐1, 4‐
diazepine‐triacetic acid, which have been introduced recently for the chelation of 68Ga …

OBJECTIVES: We developed amino acid derivatives of 1, 4, 7, 10-tetraazacyclododecane-1,
7-diacetic acid (DO2A) and 1, 4, 7, 10-tetraazacyclododecane-1, 4, 7,-triacetic acid (DO3A) …

Abstract [68Ga] Ga3+ can be introduced into receptor‐specific peptidic carriers via different
chelators to obtain radiotracers for Positron Emission Tomography imaging and the chosen …

Abstract Cyclic RGD (Arg-Gly-Asp) peptides radiolabeled with 68Ga have great potential for
the early tumor detection and noninvasive monitoring of tumor metastasis and therapeutic …

68Ga PET imaging in clinical oncology represents a notable development because the
availability of 68Ga is not dependent on a cyclotron. Furthermore, labeled amino acid …

The bioorthogonal reaction between a tetrazine and strained trans-cyclooctene (TCO) has
garnered success in pretargeted imaging. This reaction was first validated in nuclear …

Abstract 68 Ga-DOTA-peptides are a promising PET radiotracers used in the detection of
different tumours types due to their ability for binding specifically receptors overexpressed in …

Although protein-based PET imaging agents are projected to become important tracer
molecules in the future, the labeling of complex biomolecules with PET radionuclides is …