Changes in apoptosis-related gene expression profiles in cancer cell lines exposed to usnic acid lichen secondary metabolite
AB Dincsoy, DC Duman - Turkish Journal of Biology, 2017 - journals.tubitak.gov.tr
The presence of uninhibited side effects of cancer drugs often used in cancer treatment has
stimulated the search for alternative therapeutic approaches. Therefore, anticarcinogenic …
stimulated the search for alternative therapeutic approaches. Therefore, anticarcinogenic …
Usnic acid induces apoptosis in human gastric cancer cells through ROS generation and DNA damage and causes up-regulation of DNA-PKcs and γ-H2A. X …
Usnic acid, a dibenzofuran derivative found in many lichen species, is reported to have
anticancer activity against human gastric cancer. We investigated the molecular alterations …
anticancer activity against human gastric cancer. We investigated the molecular alterations …
Usnic acid: a non-genotoxic compound with anti-cancer properties
M Mayer, MA O'Neill, KE Murray… - Anti-cancer …, 2005 - journals.lww.com
The majority of human tumors bear inactive p53 or cellular factors that down-regulate the
expression and activity of the p53 network. Therefore, finding therapies that are effective in …
expression and activity of the p53 network. Therefore, finding therapies that are effective in …
Usnic acid inhibits growth and induces cell cycle arrest and apoptosis in human lung carcinoma A549 cells
Usnic acid (UA) is a secondary metabolite abundantly found in lichens. Some studies have
shown the anticancer potential of UA; however, its efficacy and associated mechanisms are …
shown the anticancer potential of UA; however, its efficacy and associated mechanisms are …
Synthesis of usnic acid derivatives and evaluation of their antiproliferative activity against cancer cells
A Pyrczak-Felczykowska, R Narlawar… - Journal of natural …, 2019 - ACS Publications
Usnic acid is a secondary metabolite abundantly found in lichens, for which promising
cytotoxic and antitumor potential has been shown. However, knowledge concerning …
cytotoxic and antitumor potential has been shown. However, knowledge concerning …
The role of usnic acid-induced apoptosis and autophagy in hepatocellular carcinoma
Usnic acid (UA) is a multifunctional bioactive lichen secondary metabolite with potential anti-
cancer properties. Although the promising therapeutic effects of UA have been investigated …
cancer properties. Although the promising therapeutic effects of UA have been investigated …
Cellular mechanisms of the anticancer effects of the lichen compound usnic acid
E Einarsdóttir, J Groeneweg, GG Björnsdóttir… - Planta …, 2010 - thieme-connect.com
The lichen compound usnic acid is used for its antimicrobial activities in cosmetic products
and is also a component of slimming agents. Its effect against cancer cells was first noted …
and is also a component of slimming agents. Its effect against cancer cells was first noted …
Lichens exerts an anti-proliferative effect on human breast and lung cancer cells through induction of apoptosis
Successful cancer treatment still requires new complexes or compounds from natural
sources. Therefore, we investigated anti-growth/apoptotic effects of methanol extracts of the …
sources. Therefore, we investigated anti-growth/apoptotic effects of methanol extracts of the …
[HTML][HTML] Usnic acid induces cycle arrest, apoptosis, and autophagy in gastric cancer cells in vitro and in vivo
X Geng, X Zhang, B Zhou, C Zhang, J Tu… - … medical journal of …, 2018 - ncbi.nlm.nih.gov
Background Usnic acid (UA), a secondary metabolite, is mainly derived from certain lichen
species. Growing evidence suggests that UA has antitumor, anti-oxidative, anti …
species. Growing evidence suggests that UA has antitumor, anti-oxidative, anti …
Genotoxic, cytotoxic, and apoptotic effects of crude extract of Usnea filipendula Stirt. in vitro
Lichens are recently receiving great attention because they have potential anticancer
activity. Therefore, in this study, genotoxic and antigrowth properties of lichen species Usnea …
activity. Therefore, in this study, genotoxic and antigrowth properties of lichen species Usnea …
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