The role of Fluoxetine against preneoplastic lesions and tumors in colon tissue
V Kannen Cardoso - 2013 - opus.bibliothek.uni-wuerzburg.de
Introduction: Colon cancer is one of the major human malignancies worldwide, and much
effort has been applied to understand the process of colon carcinogenesis, as well as the …
effort has been applied to understand the process of colon carcinogenesis, as well as the …
[HTML][HTML] Fluoxetine induces preventive and complex effects against colon cancer development in epithelial and stromal areas in rats
V Kannen, T Marini, A Turatti, MC Carvalho… - Toxicology letters, 2011 - Elsevier
Fluoxetine (FLX) is a drug commonly used as antidepressant. However, its effects on
tumorigenesis remain controversial. Aiming to evaluate the effects of FLX treatment on early …
tumorigenesis remain controversial. Aiming to evaluate the effects of FLX treatment on early …
Antiproliferative effects of fluoxetine on colon cancer cells and in a colonic carcinogen mouse model
The antidepressant fluoxetine has been under discussion because of its potential influence
on cancer risk. It was found to inhibit the development of carcinogen-induced preneoplastic …
on cancer risk. It was found to inhibit the development of carcinogen-induced preneoplastic …
Oncostatic effects of fluoxetine in experimental colon cancer models
Colon cancer is one of the most common tumors in the human population. Recent studies
have shown a reduced risk for colon cancer in patients given the antidepressant fluoxetine …
have shown a reduced risk for colon cancer in patients given the antidepressant fluoxetine …
[PDF][PDF] Antiproliferative Effects of Fluoxetine on Colon Cancer Cells and in a Colonic
The antidepressant fluoxetine has been under discussion because of its potential influence
on cancer risk. It was found to inhibit the development of carcinogen-induced preneoplastic …
on cancer risk. It was found to inhibit the development of carcinogen-induced preneoplastic …
[HTML][HTML] Antidepressant fluoxetine and its potential against colon tumors
H Stopper, SB Garcia, AM Waaga-Gasser… - World Journal of …, 2014 - ncbi.nlm.nih.gov
Colon cancer is one of the most common tumors worldwide, with increasing incidence in
developing countries. Patients treated with fluoxetine (FLX) have a reduced incidence of …
developing countries. Patients treated with fluoxetine (FLX) have a reduced incidence of …
[PDF][PDF] The role of Fluoxetine against preneoplastic lesions and tumors in colon tissue
VK Cardoso - 2013 - core.ac.uk
Fluoxetine (FLX) is a selective serotonin reuptake inhibitor (SSRI), and was discovered by a
research group from the Eli Lilly Company in 1974 [1]. It is a lipophilic weak base …
research group from the Eli Lilly Company in 1974 [1]. It is a lipophilic weak base …
Fluoxetine inhibits the extracellular signal regulated kinase pathway and suppresses growth of cancer cells
A Stepulak, W Rzeski, M Sifringer, K Brocke… - Cancer biology & …, 2008 - Taylor & Francis
Fluoxetine (FLX) is a widely prescribed antidepressant. Concerns were raised about the
potential impact of FLX on cancer growth, because FLX was shown to promote development …
potential impact of FLX on cancer growth, because FLX was shown to promote development …
[HTML][HTML] Ameliorative effect of fluvoxamine against colon carcinogenesis via COX-2 blockade with oxidative and metabolic stress reduction at the cellular, molecular …
Abstract Fluvoxamine's (FLX's) anticancer potential was investigated in pre-clinical research
utilizing a DMH-induced colorectal cancer (CRC) rat model. qRT-PCR and immunoblotting …
utilizing a DMH-induced colorectal cancer (CRC) rat model. qRT-PCR and immunoblotting …
[HTML][HTML] Probing the chemoprevention potential of the antidepressant fluoxetine combined with epigallocatechin gallate or kaempferol in rats with induced early stage …
ESG Hassan, NM Hassanein, HMS Ahmed - Journal of Pharmacological …, 2021 - Elsevier
The enhanced chemopreventive action against 1, 2 Dimethylhydrazine (DMH)-induced
preneoplastic lesion in rats could be achieved via simultaneous administration of the …
preneoplastic lesion in rats could be achieved via simultaneous administration of the …