The anaesthetic ketamine is used to treat various chronic pain syndromes, especially those
that have a neuropathic component. Low dose ketamine produces strong analgesia in …

Anecdotal reports suggest that the general anaesthetic drug ketamine, taken orally in low
doses, can give rise to some extra analgesia in patients with refractory neuropathic pain …

The analgesic effect of ketamine is primarily based on the antagonism of the N-methyl-d-
aspartate (NMDA) receptor. Activation of NMDA receptors may play a crucial role in the …

Ketamine has diverse effects that may be of relevance to chronic pain including: N-methyl-d-
aspartic acid, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid, kainate, γ …

Ketamine is a dissociative anaesthetic; its mechanism of action is primarily an antagonism of
the N-methyl-d-aspartate (NMDA) receptor. The role of ketamine, in particular in lower sub …

Ketamine is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist used
recently for analgesia in patients with chronic pain. Twenty-one patients with chronic …

Ketamine is a non-competitive antagonist to the phencyclidine site of N-methyl-d-aspartate
(NMDA) receptor for glutamate, though its effects are mediated by interaction with many …

Background This work summarizes the efficiency, failures and adverse effects of oral
administration of ketamine at home for intractable pain. Methods This 5‐year retrospective …

Importance of the field: Worldwide the number of patients affected by chronic pain is growing
and conventional treatment is often insufficient. Recently the importance of the N-methyl-d …

Objectives. Ketamine, noncompetitive antagonist of N-methyl-D-aspartate (NMDA)
receptors, has been used in the treatment of chronic neuropathic pain for almost 15 years …