Antiretroviral drug resistance profiles and response to second-line therapy among HIV type 1-infected Ugandan children

V Musiime, E Kaudha, J Kayiwa, G Mirembe… - AIDS research and …, 2013 - liebertpub.com
We sought to determine the pattern of resistance-associated mutations (RAMs) among HIV-1-
infected children failing first-line antiretroviral therapy (ART) and ascertain their response to …

high rates of thymidine analogue mutations and dual-class resistance among HIV-infected Ugandan children failing first-line antiretroviral therapy

KCE Sigaloff, J Kayiwa, V Musiime… - AIDS research and …, 2013 - liebertpub.com
HIV-infected children are at high risk of acquiring drug-resistant viruses, which is of
particular concern in settings where antiretroviral drug options are limited. We aimed to …

Drug resistance is widespread among children who receive long-term antiretroviral treatment at a rural Tanzanian hospital

C Bratholm, A Johannessen, E Naman… - Journal of …, 2010 - academic.oup.com
Objectives To assess long-term virological efficacy and the emergence of drug resistance in
children who receive antiretroviral treatment (ART) in rural Tanzania. Patients and methods …

HIV drug resistance among children initiating first-line antiretroviral treatment in Uganda

C Kityo, KCE Sigaloff, TS Boender… - AIDS research and …, 2016 - liebertpub.com
Background: There are limited data on primary human immunodeficiency virus drug
resistance (HIVDR) in pediatric populations. This study aimed to assess the prevalence of …

Development of HIV drug resistance and therapeutic failure in children and adolescents in rural Tanzania: an emerging public health concern

L Muri, A Gamell, AJ Ntamatungiro, TR Glass… - Aids, 2017 - journals.lww.com
Objective: To investigate the prevalence and determinants of virologic failure and acquired
drug resistance-associated mutations (DRMs) in HIV-infected children and adolescents in …

Anti‐retroviral drug resistance‐associated mutations among non‐subtype B HIV‐1‐infected Kenyan children with treatment failure

R Lwembe, W Ochieng, A Panikulam… - Journal of medical …, 2007 - Wiley Online Library
Recently increased availability of anti‐retroviral therapy (ART) has mitigated HIV‐1/AIDS
prognoses especially in resource poor settings. The emergence of ART resistance …

Incidence and risk factors for first line anti retroviral treatment failure among Ugandan children attending an urban HIV clinic

R Sebunya, V Musiime, SB Kitaka, G Ndeezi - AIDS research and therapy, 2013 - Springer
Background Early recognition of antiretroviral therapy (ART) failure in resource limited
settings is a challenge given the limited laboratory facilities and trained personnel. This …

Virological response and resistance profiles after 18 to 30 months of first-or second-/third-line antiretroviral treatment: a cross-sectional evaluation in HIV type 1 …

C Charpentier, JC Gody, O Mbitikon… - AIDS research and …, 2012 - liebertpub.com
Abstract A total of 242 HIV-1-infected children were followed up at the Complexe Pédiatrique
of Bangui, Central African Republic, including 165 receiving antiretroviral treatment in first …

Antiretroviral drug susceptibility among HIV-infected adults failing antiretroviral therapy in Rakai, Uganda

SJ Reynolds, O Laeyendecker, G Nakigozi… - AIDS research and …, 2012 - liebertpub.com
We analyzed antiretroviral drug susceptibility in HIV-infected adults failing first-and second-
line antiretroviral treatment (ART) in Rakai, Uganda. Samples obtained from participants at …

Drug resistance in children at virological failure in a rural KwaZulu-Natal, South Africa, cohort

S Pillay, RM Bland, RJ Lessells, J Manasa… - AIDS research and …, 2014 - Springer
Background Better understanding of drug resistance patterns in HIV-infected children on
antiretroviral therapy (ART) is required to inform public health policies in high prevalence …