Abstract Background In sub-Saharan Africa, data on virologic outcomes of young people
living with HIV (YLWH) enrolled on antiretroviral therapy (ART) remains scarce. In this study …

In view of the recent antiretroviral therapy (ART) scale-up in Kenya, surveillance of
transmitted HIV drug resistance (TDR) is important. A cross-sectional survey was conducted …

Background. Emergence of human immunodeficiency virus type 1 (HIV-1) drug resistance
may limit the benefits of antiretroviral therapy in resource-limited settings. The prevalence of …

Objective To evaluate the longer-term utility of genotypic resistance testing in HIV-1-infected
children with virological failure. Methods Children aged 3 months-18 years switching …

From 2006 to 2011, a cohort study was conducted among 1000 children resident in urban
and rural settings of Uganda to ascertain and compare the response to antiretroviral therapy …

Background: HIV-infected children may require the use of combination antiretroviral
treatment (cART) into adulthood. However, regimens are limited to first line and second line …

Few reports have examined the impact of HIV-1 transmitted drug resistance (TDR) in
resource-limited settings where there are fewer regimen choices and limited pretherapy …

Objectives South Africa's national antiretroviral (ARV) treatment program expanded in 2010
to include the nucleoside reverse transcriptase (RT) inhibitors (NRTI) tenofovir (TDF) for …

Clinical monitoring of pediatric HIV treatment remains a major challenge in settings where
drug resistance genotyping is not routinely available. As a result, our understanding of drug …

Objective To evaluate HIV drug resistance (HIVDR) and determinants of virological failure in
a large cohort of patients receiving first‐line tenofovir‐based antiretroviral therapy (ART) …