Structural Analyses of the Ankyrin Repeat Domain of TRPV6 and Related TRPV Ion Channels,

CB Phelps, RJ Huang, PV Lishko, RR Wang… - Biochemistry, 2008 - ACS Publications
Transient receptor potential (TRP) proteins are cation channels composed of a
transmembrane domain flanked by large N-and C-terminal cytoplasmic domains. All …

Trpv1

S Bevan, T Quallo, DA Andersson - Mammalian Transient Receptor …, 2014 - Springer
TRPV1 is a well-characterised channel expressed by a subset of peripheral sensory
neurons involved in pain sensation and also at a number of other neuronal and non …

TRPV1 function in health and disease

J PM White, L Urban, I Nagy - Current pharmaceutical …, 2011 - ingentaconnect.com
The transient receptor potential vanilloid type 1 ion channel (TRPV1) was identified as a
receptor responsible for mediating the intense burning sensation following exposure to heat …

[HTML][HTML] Role of the TRPV channels in the endoplasmic reticulum calcium homeostasis

A Haustrate, N Prevarskaya, V Lehen'kyi - Cells, 2020 - mdpi.com
It has been widely established that transient receptor potential vanilloid (TRPV) channels
play a crucial role in calcium homeostasis in mammalian cells. Modulation of TRPV …

[HTML][HTML] Conserved residues within the putative S4–S5 region serve distinct functions among thermosensitive vanilloid transient receptor potential (TRPV) channels

S Boukalova, L Marsakova, J Teisinger… - Journal of Biological …, 2010 - ASBMB
The vanilloid transient receptor potential channel TRPV1 is a tetrameric six-transmembrane
segment (S1–S6) channel that can be synergistically activated by various proalgesic agents …

Biochemical pharmacology of the vanilloid receptor TRPV1: an update

DN Cortright, A Szallasi - European journal of biochemistry, 2004 - Wiley Online Library
There is mounting evidence that the vanilloid (capsaicin) receptor; transient receptor
potential channel, vanilloid subfamily member 1 (TRPV1), is subjected to multiple interacting …

[HTML][HTML] Structural bases of TRP channel TRPV6 allosteric modulation by 2-APB

AK Singh, K Saotome, LL McGoldrick… - Nature …, 2018 - nature.com
Transient receptor potential (TRP) channels are involved in various physiological processes,
including sensory transduction. The TRP channel TRPV6 mediates calcium uptake in …

Functional role of C-terminal cytoplasmic tail of rat vanilloid receptor 1

V Vlachová, J Teisinger, K Sušánková… - Journal of …, 2003 - Soc Neuroscience
The vanilloid receptor [transient receptor potential (TRP) V1, also known as VR1] is a
member of the TRP channel family. These receptors share a significant sequence homology …

[HTML][HTML] Differential regulation of TRPV1, TRPV3, and TRPV4 sensitivity through a conserved binding site on the ankyrin repeat domain

CB Phelps, RR Wang, SS Choo, R Gaudet - Journal of Biological Chemistry, 2010 - ASBMB
Transient receptor potential vanilloid (TRPV) channels, which include the thermosensitive
TRPV1–V4, have large cytoplasmic regions flanking the transmembrane domain, including …

Vanilloid transient receptor potential cation channels: an overview

B Nilius, R Vennekens… - Current pharmaceutical …, 2008 - ingentaconnect.com
The mammalian branch of the Transient Receptor Potential (TRP) superfamily of cation
channels consists of 28 members. They can be subdivided in six main subfamilies: the …