The pharmacological challenge to tame the transient receptor potential vanilloid‐1 (TRPV1) nocisensor
P Holzer - British journal of pharmacology, 2008 - Wiley Online Library
The transient receptor potential vanilloid‐1 (TRPV1) cation channel is a receptor that is
activated by heat (> 42° C), acidosis (pH< 6) and a variety of chemicals among which …
activated by heat (> 42° C), acidosis (pH< 6) and a variety of chemicals among which …
Calcium selective channel TRPV6: Structure, function, and implications in health and disease
Calcium-selective channel TRPV6 (Transient Receptor Potential channel family, Vanilloid
subfamily member 6) belongs to the TRP family of cation channels and plays critical roles in …
subfamily member 6) belongs to the TRP family of cation channels and plays critical roles in …
The vanilloid receptor TRPV1: role in cardiovascular and gastrointestinal protection
J Peng, YJ Li - European journal of pharmacology, 2010 - Elsevier
It has been shown that the transient receptor potential channel vanilloid type 1 (TRPV1) is
able to sense a vast range of stimuli and exerts multiple functions under physiological or …
able to sense a vast range of stimuli and exerts multiple functions under physiological or …
TRPV4 and the regulation of vascular tone
Recent studies have introduced the importance of transient receptor potential vanilloid
subtype 4 (TRPV4) channels in the regulation of vascular tone. TRPV4 channels are …
subtype 4 (TRPV4) channels in the regulation of vascular tone. TRPV4 channels are …
TRPV4 channels: physiological and pathological role in cardiovascular system
PK Randhawa, AS Jaggi - Basic research in cardiology, 2015 - Springer
TRPV4 channels are non-selective cation channels permeable to Ca 2+, Na+, and Mg 2+
ions. Recently, TRPV4 channels have received considerable attention as these channels …
ions. Recently, TRPV4 channels have received considerable attention as these channels …
Hysteresis of gating underlines sensitization of TRPV3 channels
Vanilloid receptors of the transient receptor potential family have functions in thermal
sensation and nociception. Among them, transient receptor potential vanilloid (TRPV) 3 …
sensation and nociception. Among them, transient receptor potential vanilloid (TRPV) 3 …
N-((1S)-1-{[4-((2S)-2-{[(2, 4-dichlorophenyl) sulfonyl] amino}-3-hydroxypropanoyl)-1-piperazinyl] carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide …
KS Thorneloe, AC Sulpizio, Z Lin, DJ Figueroa… - … of Pharmacology and …, 2008 - ASPET
The transient receptor potential (TRP) vanilloid 4 (TRPV4) member of the TRP superfamily
has recently been implicated in numerous physiological processes. In this study, we …
has recently been implicated in numerous physiological processes. In this study, we …
Systemic activation of the transient receptor potential vanilloid subtype 4 channel causes endothelial failure and circulatory collapse: Part 2
RN Willette, W Bao, S Nerurkar, T Yue, CP Doe… - … of Pharmacology and …, 2008 - ASPET
The transient receptor potential (TRP) vanilloid subtype 4 (V4) is a nonselective cation
channel that exhibits polymodal activation and is expressed in the endothelium, where it …
channel that exhibits polymodal activation and is expressed in the endothelium, where it …
Regulation of the murine TRPP3 channel by voltage, pH, and changes in cell volume
Transient receptor potential (TRP) polycystin 3 (TRPP3) is a member of the TRP superfamily
of cation channels. Murine TRPP3 has been reported to form an acid-activated cation …
of cation channels. Murine TRPP3 has been reported to form an acid-activated cation …
[HTML][HTML] Structural insights on TRPV5 gating by endogenous modulators
TET Hughes, RA Pumroy, AT Yazici… - Nature …, 2018 - nature.com
TRPV5 is a transient receptor potential channel involved in calcium reabsorption. Here we
investigate the interaction of two endogenous modulators with TRPV5. Both …
investigate the interaction of two endogenous modulators with TRPV5. Both …