Pregabalin, a compound with a novel mechanism of action (MOA), has demonstrated
efficacy as an adjunctive treatment for epilepsy and in several neuropathic pain models …

Pregabalin is a potent ligand for the alpha‐2‐delta subunit of voltage‐gated calcium
channels in the central nervous system that exhibits potent anticonvulsant, analgesic, and …

Pregabalin is a new synthetic molecule and a structural derivative of the inhibitory
neurotransmitter γ-aminobutyric acid. It is an α 2-δ (α 2-δ) ligand that has analgesic …

Pregabalin (S-[+]-3-isobutylgaba) was designed as a lipophilic GABA (γ-aminobutyric acid)
analogue substituted at the 3′-position in order to facilitate diffusion across the blood–brain …

Abstract▲ Pregabalin, the pharmacologically active S-enantiomer of 3-aminomethyl-5-
methyl-hexanoic acid, is a structural analogue of GABA, although it is not active at GABA …

Pregabalin is a specific ligand of the alpha 2-delta (α 2-δ) auxiliary subunit of voltage-gated
calcium channels. A growing body of evidence from studies of anxiety and pain indicate that …

Pregabalin (Lyrica™) is a new antiepileptic drug that is active in animal seizure models.
Pregabalin is approved in US and Europe for adjunctive therapy of partial seizures in adults …

Pregabalin is a recently licensed and marketed antiepileptic drug for use as adjunctive
treatment of partial epilepsy. It acts at presynaptic calcium channels, modulating …

BACKGROUND:: The US Food and Drug Administration (FDA) approved pregabalin in
December 2004 for the treatment of neuropathic pain associated with diabetic peripheral …

Pregabalin is an anticonvulsant drug that binds to the α2δ (alpha2delta) subunit of the
voltage-dependent calcium channel in central nervous system (CNS). Pregabalin decreases …