Anti-inflammatory and anti-nociceptive effects of strontium ranelate on the zymosan-induced temporomandibular joint inflammatory hypernociception in rats depend …
SM Alves, SC Abreu, JC Lemos, FIF Gomes… - Pharmacological …, 2017 - Elsevier
Background Temporomandibular joint (TMJ) disorders show inflammatory components,
heavily impacting on quality of life. Strontium ranelate has previously shown anti …
heavily impacting on quality of life. Strontium ranelate has previously shown anti …
Regulation of the trigeminal NR1 subunit expression induced by inflammation of the temporomandibular joint region in rats
Expression of the N-methyl-d-aspartate (NMDA) receptor in trigeminal nuclei has been
shown to play a role in the mechanisms of trigeminal pain. Here, we examined the …
shown to play a role in the mechanisms of trigeminal pain. Here, we examined the …
The Role of Nav1.9 Channel in the Development of Neuropathic Orofacial Pain Associated with Trigeminal Neuralgia
AP Lulz, O Kopach, S Santana-Varela… - Molecular …, 2015 - journals.sagepub.com
Background Trigeminal neuralgia is accompanied by severe mechanical, thermal and
chemical hypersensitivity of the orofacial area innervated by neurons of trigeminal ganglion …
chemical hypersensitivity of the orofacial area innervated by neurons of trigeminal ganglion …
Involvement of transient receptor potential vanilloid 1 channel expression in orofacial cutaneous hypersensitivity following tooth pulp inflammation
T Watase, K Shimizu, H Komiya, K Ohara… - Journal of Oral …, 2018 - jstage.jst.go.jp
A study was conducted to evaluate the mechanisms underlying ectopic orofacial pain
associated with tooth pulp inflammation in rats. We observed a significant decrease in the …
associated with tooth pulp inflammation in rats. We observed a significant decrease in the …
Participation of peripheral tachykinin NK1 receptors in the carrageenan-induced inflammation of the rat temporomandibular joint
A Denadai-Souza, L de Lucca Camargo… - European Journal of …, 2009 - Elsevier
Temporomandibular disorders represent one of the major challenges in dentistry
therapeutics. This study was undertaken to evaluate the time course of carrageenan …
therapeutics. This study was undertaken to evaluate the time course of carrageenan …
Temporomandibular joint inflammation decreases the voltage-gated K+ channel subtype 1.4-immunoreactivity of trigeminal ganglion neurons in rats
M Takeda, T Tanimoto, M Nasu, S Matsumoto - European journal of pain, 2008 - Elsevier
Voltage-gated K+ (Kv) channels are one of the important physiological regulators of the
membrane potentials in excitable cells, including sensory ganglion neurons. The aim of the …
membrane potentials in excitable cells, including sensory ganglion neurons. The aim of the …
N-methyl-D-aspartate Receptor Subunits 2A and 2B Mediate Connexins and Pannexins in the Trigeminal Ganglion Involved in Orofacial Inflammatory Allodynia …
YL Li, YY Zhang, QX Song, F Liu, YJ Liu, YK Li… - Molecular …, 2024 - Springer
Temporomandibular joint osteoarthritis (TMJOA) is a severe form of temporomandibular joint
disorders (TMD), and orofacial inflammatory allodynia is one of its common symptoms which …
disorders (TMD), and orofacial inflammatory allodynia is one of its common symptoms which …
Inhibition of TNF reduces mechanical orofacial hyperalgesia induced by Complete Freund's Adjuvant by a TRPV1-dependent mechanism in mice
K Lis, T Grygorowicz, A Cudna, DE Szymkowski… - Pharmacological …, 2017 - Elsevier
Background Inflammation in the orofacial region results in pain and is associated with many
pathological states, including migraine, neuralgias and temporomandibular disorder …
pathological states, including migraine, neuralgias and temporomandibular disorder …
Changes in the expression of voltage-gated sodium channels Nav1. 3, Nav1. 7, Nav1. 8, and Nav1. 9 in rat trigeminal ganglia following chronic constriction injury
W Xu, J Zhang, Y Wang, L Wang, X Wang - Neuroreport, 2016 - journals.lww.com
Voltage-gated sodium channels (VGSCs), especially the tetrodotoxin-sensitive Na v 1.3 and
Na v 1.7, and the tetrodotoxin-resistant Na v 1.8 and Na v 1.9, have been implicated in acute …
Na v 1.7, and the tetrodotoxin-resistant Na v 1.8 and Na v 1.9, have been implicated in acute …
Quercetin, Main Active Ingredient of Moutan Cortex, Alleviates Chronic Orofacial Pain via Block of Voltage-Gated Sodium Channel
Z Liu, Z Shan, H Yang, Y Xing, W Guo… - Anesthesia & …, 2024 - journals.lww.com
BACKGROUND: Chronic orofacial pain (COP) therapy is challenging, as current medical
treatments are extremely lacking. Moutan Cortex (MC) is a traditional Chinese medicine …
treatments are extremely lacking. Moutan Cortex (MC) is a traditional Chinese medicine …