Next generation cancer vaccines—make it personal!

A Terbuch, J Lopez - Vaccines, 2018 - mdpi.com
Dramatic success in cancer immunotherapy has been achieved over the last decade with
the introduction of checkpoint inhibitors, leading to response rates higher than with …

Next-generation cancer vaccines and emerging immunotherapy combinations

A Brandenburg, A Heine, P Brossart - Trends in Cancer, 2024 - cell.com
Therapeutic cancer vaccines have been a subject of research for several decades as
potential new weapons to tackle malignancies. Their goal is to induce a long-lasting and …

[HTML][HTML] Strategies for developing and optimizing cancer vaccines

HM Maeng, JA Berzofsky - F1000Research, 2019 - ncbi.nlm.nih.gov
With the spotlight on cancer immunotherapy and the expanding use of immune checkpoint
inhibitors, strategies to improve the response rate and duration of current cancer …

Personalized cancer vaccines pass first major clinical test

E Dolgin - Nat Rev Drug Discov, 2023 - nature.com
The findings, reported earlier this year, have revitalized the cancer vaccine community,
inspiring companies to intensify efforts to stimulate the immune system to recognize tumour …

Therapeutic cancer vaccines: how much closer are we?

DG McNeel - BioDrugs, 2018 - Springer
The promise of immune-based therapies to treat cancer has been realized over the last
several years with several breakthrough therapies, including T-cell checkpoint inhibitors and …

Cancer vaccines: Enhanced immunogenic modulation through therapeutic combinations

ME Gatti-Mays, JM Redman, JM Collins… - Human vaccines & …, 2017 - Taylor & Francis
Therapeutic cancer vaccines have gained significant popularity in recent years as new
approaches for specific oncologic indications emerge. Three therapeutic cancer vaccines …

[HTML][HTML] Next generation approaches for tumor vaccination

A Patel, HL Kaufman, ML Disis - Chinese clinical oncology, 2017 - cco.amegroups.org
Tumor vaccines have been an attractive concept in the immunotherapy of cancer based on
the central role of tumor-associated antigens in allowing the immune system to recognize …

The Promise of immunotherapeutics and vaccines in the treatment of cancer

A Gaur, N Chirmule - Handbook of Oncobiology: From Basic to Clinical …, 2023 - Springer
Abstract The Cancer Moonshot aspires to cut the death rate from cancer by at least 50%
over the next 25 years by 2047 and improve the experience of people and their families …

Perspective: cancer vaccines in the era of immune checkpoint blockade

J Cebon - Mammalian Genome, 2018 - Springer
Current excitement about cancer immunotherapy is the result of unprecedented clinical
impact from immune checkpoint inhibitors, particularly those that target programmed death …

Personalized approaches to active immunotherapy in cancer

E Ophir, S Bobisse, G Coukos, A Harari… - Biochimica et Biophysica …, 2016 - Elsevier
Immunotherapy is emerging as a promising anti-cancer curative modality. However, in
contrast to recent advances obtained employing checkpoint blockade agents and T cell …