Background A new lateral flow immunoassay (LFA) for the detection of cryptococcal antigen
was developed. Objective We aimed to systematically review all relevant studies to evaluate …

Background The incidence of cryptococcosis amongst HIV-negative persons is increasing.
Whilst the excellent performance of the CrAg testing in people living with HIV is well …

Background. Cryptococcosis is a common opportunistic infection of human
immunodeficiency virus (HIV)–infected individuals mostly occurring in resource-limited …

Importance of field: Cryptococcal meningitis is a leading cause of death globally among
people with AIDS. In sub-Saharan Africa, cryptococcosis is estimated to kill more people …

Methods We conducted a review of published literature and conference abstracts through
August 21, 2012, to identify studies on the performance of the LFA in serum and CSF …

Background Cryptococcus neoformans causes life-threatening meningitis. A recently
introduced lateral flow immunoassay (LFA) to detect cryptococcal antigen (CRAG) is …

Cryptococcal meningitis is a devastating HIV-related opportunistic infection, affecting nearly
1 million individuals and causing over 500 000 deaths each year. The burden of disease is …

ABSTRACT Detection of Cryptococcus antigen (CrAg) is invaluable for establishing
cryptococcal disease. Multiple different methods for CrAg detection are available, including …

Cryptococcal meningitis is a leading cause of meningitis in sub-Saharan Africa. Given the
need for rapid point-of-care testing, we evaluated the diagnostic performance of the …

Early cryptococcal disease can be detected via circulating antigen in blood before fulminant
meningitis develops, when early antifungal therapy improves survival. Two semiquantitative …