Francisella tularensis is a Gram-negative intracellular pathogen and the causative agent of
the disease tularemia. Inhalation of as few as 10 bacteria is sufficient to cause severe …

Tularemia is a zoonosis of humans caused by infection with the facultative intracellular
bacterium Francisella tularensis. Interest in F. tularensis has increased markedly in the past …

ABSTRACT A safer and more effective vaccine than the previously developed live
attenuated vaccine is needed for combating Francisella tularensis, a highly infectious …

Francisella tularensis is a bacterial pathogen that causes the zoonotic disease tularemia
and is important to biodefense. Currently, the only vaccine known to confer protection …

Tularemia is primarily caused by two subspecies of Francisella tularensis worldwide, ssp.
tularensis (type A) and ssp. holarctica (type B), which were originally delineated by …

Francisella tularensis is a highly-infectious bacterium that causes the rapid, and often lethal
disease, tularemia. Many studies have been performed to identify and characterize the …

The γ-proteobacterium Francisella tularensis is one of the most infectious human pathogens,
and the highly virulent organism F. tularensis subsp. tularensis (type A) and less virulent …

This unit describes the utility of various mouse models of infection for studying pathogenesis
and adaptive immune responses to the facultative intracellular bacteria pathogen …

Francisella tularensis is a Gram-negative facultative intracellular pathogen and the
causative agent of tularemia. Recently, genome-wide screens have identified Francisella …

Francisella tularensis is a highly virulent bacterial pathogen that invades and replicates
within numerous host cell types, including macrophages and epithelial cells. In an effort to …