Comparative Genomic Characterization of Francisella tularensis Strains Belonging to Low and High Virulence Subspecies

MD Champion, Q Zeng, EB Nix, FE Nano… - PLoS …, 2009 - journals.plos.org
Tularemia is a geographically widespread, severely debilitating, and occasionally lethal
disease in humans. It is caused by infection by a gram-negative bacterium, Francisella …

Francisella tularensis subsp. novicida isolated from a human in Arizona

DN Birdsell, T Stewart, AJ Vogler, E Lawaczeck… - BMC Research …, 2009 - Springer
Background Francisella tularensis is the etiologic agent of tularemia and is classified as a
select agent by the Centers for Disease Control and Prevention. Currently four known …

Regulation of Francisella Tularensis Virulence

S Dai, NP Mohapatra, LS Schlesinger… - Frontiers in …, 2011 - frontiersin.org
Francisella tularensis is one of the most virulent bacteria known and a Centers for Disease
Control and Prevention Category A select agent. It is able to infect a variety of animals and …

A Francisella tularensis Live Vaccine Strain (LVS) Mutant with a Deletion in capB, Encoding a Putative Capsular Biosynthesis Protein, Is Significantly More Attenuated than LVS …

Q Jia, BY Lee, R Bowen, BJ Dillon, SM Som… - Infection and …, 2010 - Am Soc Microbiol
Francisella tularensis, the causative agent of tularemia, is in the top category (category A) of
potential agents of bioterrorism. The F. tularensis live vaccine strain (LVS) is the only …

Identification of an Essential Francisella tularensis subsp. tularensis Virulence Factor

A Qin, DW Scott, JA Thompson, BJ Mann - Infection and immunity, 2009 - Am Soc Microbiol
Francisella tularensis, the highly virulent etiologic agent of tularemia, is a low-dose
intracellular pathogen that is able to escape from the phagosome and replicate in the …

Humoral and cell‐mediated immunity to the intracellular pathogen Francisella tularensis

GS Kirimanjeswara, S Olmos, CS Bakshi… - Immunological …, 2008 - Wiley Online Library
Francisella tularensis can cause fatal respiratory tularemia in humans and animals and is
increasingly being isolated in the United States and several European countries. The …

[HTML][HTML] The Francisella intracellular life cycle: toward molecular mechanisms of intracellular survival and proliferation

A Chong, J Celli - Frontiers in microbiology, 2010 - frontiersin.org
The tularemia-causing bacterium Francisella tularensis is a facultative intracellular organism
with a complex intracellular lifecycle that ensures its survival and proliferation in a variety of …

[HTML][HTML] Phylogenetic Lineages of Francisella tularensis in Animals

P Pilo - Frontiers in cellular and infection microbiology, 2018 - frontiersin.org
Tularemia is a zoonotic disease caused by the facultative intracellular bacterium Francisella
tularensis. This microorganism can infect a plethora of animal species and its ecology is …

Francisella Tularensis Metabolism and its Relation to Virulence

KL Meibom, A Charbit - Frontiers in microbiology, 2010 - frontiersin.org
Francisella tularensis is a Gram-negative bacterium capable of causing the zoonotic disease
tularaemia in a large number of mammalian species and in arthropods. F. tularensis is a …

Virulence Differences Among Francisella tularensis Subsp. tularensis Clades in Mice

CR Molins, MJ Delorey, BM Yockey, JW Young… - PLoS …, 2010 - journals.plos.org
Francisella tularensis subspecies tularensis (type A) and holarctica (type B) are of clinical
importance in causing tularemia. Molecular typing methods have further separated type A …