Th17 cells and inflammation in neurological disorders: Possible mechanisms of action

Y Shi, B Wei, L Li, B Wang, M Sun - Frontiers in immunology, 2022 - frontiersin.org
Neurological disorders (NDs) are one of the leading causes of global death. A sustained
neuroinflammatory response has been reported to be associated with the pathogenesis of …

The role of Th17 cells in auto-inflammatory neurological disorders

F Tahmasebinia, A Pourgholaminejad - Progress in Neuro …, 2017 - Elsevier
The role of T helper 17 (Th17) cells in auto-inflammatory neurological disorders such as
Multiple Sclerosis (MS), Alzheimer's disease (AD), Parkinson's disease (PD) and …

TH17 cytokines in autoimmune neuro-inflammation

B Becher, BM Segal - Current opinion in immunology, 2011 - Elsevier
It has been firmly established that IL-23 polarized TH17 cells are potent effectors in the
pathogenesis of experimental autoimmune encephalitomyelitis (EAE). However, the relative …

Th17 and cognitive impairment: possible mechanisms of action

V Cipollini, J Anrather, F Orzi, C Iadecola - Frontiers in neuroanatomy, 2019 - frontiersin.org
T helper 17 (Th17) cells represent a distinct population of immune cells, important in the
defense of the organism against extracellular infectious agents. Because of their cytokine …

Th17 cell, the new player of neuroinflammatory process in multiple sclerosis

F Jadidi‐Niaragh, A Mirshafiey - Scandinavian journal of …, 2011 - Wiley Online Library
Multiple sclerosis (MS) is an autoimmune disease characterized by recurrent episodes of
demyelination and axonal lesion mediated by CD4+ T cells with a proinflammatory Th1 and …

Role of Th17 cells in the pathogenesis of CNS inflammatory demyelination

A Rostami, B Ciric - Journal of the neurological sciences, 2013 - Elsevier
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS). The
etiology of MS is not well understood, but it is believed that myelin-specific CD4+ T cells play …

Current views on the roles of Th1 and Th17 cells in experimental autoimmune encephalomyelitis

M El-behi, A Rostami, B Ciric - Journal of Neuroimmune Pharmacology, 2010 - Springer
Multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis
(EAE), are autoimmune demyelinating diseases of the central nervous system (CNS) …

The role of Th17 cells/IL-17A in AD, PD, ALS and the strategic therapy targeting on IL-17A

J Fu, Y Huang, T Bao, C Liu, X Liu, X Chen - Journal of Neuroinflammation, 2022 - Springer
Neurodegenerative diseases are a group of disorders characterized by progressive loss of
certain populations of neurons, which eventually lead to dysfunction. These diseases …

Roles of T helper 17 cells and interleukin‐17 in neuroautoimmune diseases with emphasis on multiple sclerosis and Guillain‐Barré syndrome as well as their animal …

X Wang, C Ma, J Wu, J Zhu - Journal of Neuroscience …, 2013 - Wiley Online Library
The identification of T helper 17 (Th17) cells challenges the Th1/Th2 paradigm of the
immune response and invites intensive exploration of their mechanisms and functions in the …

Th17 cells in central nervous system autoimmunity

C Sie, T Korn, M Mitsdoerffer - Experimental neurology, 2014 - Elsevier
Multiple sclerosis (MS) is the most important autoimmune disease of the central nervous
system (CNS). Its animal model experimental autoimmune encephalomyelitis (EAE) has …