Evidence for core exosome independent function of the nuclear exoribonuclease Rrp6p
KP Callahan, JS Butler - Nucleic acids research, 2008 - academic.oup.com
The RNA exosome processes and degrades RNAs in archaeal and eukaryotic cells.
Exosomes from yeast and humans contain two active exoribonuclease components, Rrp6p …
Exosomes from yeast and humans contain two active exoribonuclease components, Rrp6p …
The CR3 motif of Rrp44p is important for interaction with the core exosome and exosome function
The 10-subunit RNA exosome is involved in a large number of diverse RNA processing and
degradation events in eukaryotes. These reactions are carried out by the single catalytic …
degradation events in eukaryotes. These reactions are carried out by the single catalytic …
Reconstitution of RNA exosomes from human and Saccharomyces cerevisiae: cloning, expression, purification, and activity assays
JC Greimann, CD Lima - Methods in enzymology, 2008 - Elsevier
Eukaryotic RNA exosomes participate in 3′ to 5′‐processing and degradation of RNA in
the nucleus and cytoplasm. RNA exosomes are multisubunit complexes composed of at …
the nucleus and cytoplasm. RNA exosomes are multisubunit complexes composed of at …
[HTML][HTML] Reconstitution, activities, and structure of the eukaryotic RNA exosome
The RNA exosome is a multisubunit 3′ to 5′ exoribonuclease complex that participates in
degradation and processing of cellular RNA. To determine the activities and structure of the …
degradation and processing of cellular RNA. To determine the activities and structure of the …
The Rrp6 C-terminal domain binds RNA and activates the nuclear RNA exosome
EV Wasmuth, CD Lima - Nucleic acids research, 2017 - academic.oup.com
The eukaryotic RNA exosome is an essential, multi-subunit complex that catalyzes RNA
turnover, maturation, and quality control processes. Its non-catalytic donut-shaped core …
turnover, maturation, and quality control processes. Its non-catalytic donut-shaped core …
[HTML][HTML] TRAMP complex enhances RNA degradation by the nuclear exosome component Rrp6 2
KP Callahan, JS Butler - Journal of Biological Chemistry, 2010 - ASBMB
The RNA-processing exosome contains ribonucleases that degrade aberrant RNAs in
archael and eukaryotic cells. In Saccharomyces cerevisiae, the nuclear/nucleolar 3′–5 …
archael and eukaryotic cells. In Saccharomyces cerevisiae, the nuclear/nucleolar 3′–5 …
Dis3‐like 1: a novel exoribonuclease associated with the human exosome
RHJ Staals, AW Bronkhorst, G Schilders… - The EMBO …, 2010 - embopress.org
The exosome is an exoribonuclease complex involved in the degradation and maturation of
a wide variety of RNAs. The nine‐subunit core of the eukaryotic exosome is catalytically …
a wide variety of RNAs. The nine‐subunit core of the eukaryotic exosome is catalytically …
The exosome contains domains with specific endoribonuclease, exoribonuclease and cytoplasmic mRNA decay activities
The eukaryotic exosome is a ten-subunit 3′ exoribonucleolytic complex responsible for
many RNA-processing and RNA-degradation reactions. How the exosome accomplishes …
many RNA-processing and RNA-degradation reactions. How the exosome accomplishes …
Rrp47p is an exosome-associated protein required for the 3′ processing of stable RNAs
P Mitchell, E Petfalski, R Houalla… - … and cellular biology, 2003 - Am Soc Microbiol
Related exosome complexes of 3′→ 5′ exonucleases are present in the nucleus and the
cytoplasm. Purification of exosome complexes from whole-cell lysates identified a Mg 2+ …
cytoplasm. Purification of exosome complexes from whole-cell lysates identified a Mg 2+ …
Exosome substrate targeting: the long and short of it
P Mitchell - Biochemical Society Transactions, 2014 - portlandpress.com
The exosome ribonuclease complex functions in both the limited trimming of the 3′-ends of
nuclear substrates during RNA processing events and the complete destruction of nuclear …
nuclear substrates during RNA processing events and the complete destruction of nuclear …