Time‐and dose‐dependent association of statin use with risk of clinically relevant new‐onset diabetes mellitus in primary prevention: a nationwide observational …

MJ Ko, AJ Jo, YJ Kim, SH Kang, S Cho… - Journal of the …, 2019 - Am Heart Assoc
Background Given that statins are increasingly being used for primary‐prevention, the public
concerns regarding the risk of new‐onset diabetes mellitus associated with statin use may …

Use of statins and the risk of incident diabetes: a retrospective cohort study

BS Olotu, MD Shepherd, S Novak, KA Lawson… - American Journal of …, 2016 - Springer
Introduction Even though several landmark statin trials have demonstrated the beneficial
effects of statin therapy in both primary and secondary prevention of cardiovascular disease …

Statin use and risk of developing diabetes: results from the Diabetes Prevention Program

JP Crandall, K Mather, SN Rajpathak… - BMJ Open Diabetes …, 2017 - drc.bmj.com
Objective Several clinical trials of cardiovascular disease prevention with statins have
reported increased risk of type 2 diabetes (T2DM) with statin therapy. However, participants …

[HTML][HTML] Statins and new-onset diabetes mellitus and diabetic complications: a retrospective cohort study of US healthy adults

I Mansi, CR Frei, CP Wang, EM Mortensen - Journal of general internal …, 2015 - Springer
Background Statin use is associated with increased incidence of diabetes and possibly with
increased body weight and reduced exercise capacity. Data on the long-term effects of these …

Risk of new-onset diabetes associated with statin use

RD Beckett, SM Schepers… - SAGE Open Medicine, 2015 - journals.sagepub.com
Objective: To identify and assess studies investigating the association between statins and
new-onset diabetes and determine the clinical significance of this risk. Data sources: A …

[HTML][HTML] Time-varying and dose-dependent effect of long-term statin use on risk of type 2 diabetes: a retrospective cohort study

E Na, S Cho, DJ Kim, J Choi, E Han - Cardiovascular diabetology, 2020 - Springer
Background We evaluated the effect of statin use on new-onset type 2 diabetes among
individuals without atherosclerotic cardiovascular disease (ASCVD) using nationally …

[HTML][HTML] Risk of new-onset diabetes among patients treated with statins according to hypertension and gender: Results from a nationwide health-screening cohort

SE Lee, JM Sung, IJ Cho, HC Kim, HJ Chang - PloS one, 2018 - journals.plos.org
Background Statins have been known to increase the risk of incident type 2 diabetes
mellitus (DM); however, other factors, especially hypertension, are also associated with DM …

Statins, risk of diabetes, and implications on outcomes in the general population

KL Wang, CJ Liu, TF Chao, CM Huang, CH Wu… - Journal of the American …, 2012 - jacc.org
Objectives: This study aimed to evaluate the association of statin exposure and incident
diabetes, and subsequent outcomes in the general population. Background: Cardiovascular …

Balancing primary prevention and statin-induced diabetes mellitus prevention

Y Rochlani, AJ Kattoor, NV Pothineni… - The American journal of …, 2017 - Elsevier
Diabetes mellitus (DM), a modern-day epidemic, is a significant risk factor for cardiovascular
disease. It is believed that statins elevate the risk of incident DM. Multiple trials were …

Long-term outcomes of short-term statin use in healthy adults: a retrospective cohort study

IA Mansi, J English, S Zhang, EM Mortensen, EA Halm - Drug safety, 2016 - Springer
Introduction Data suggest that the beneficial cardiovascular effects of statins are maximized
after the first year of statin use; yet, the timeline of statin-associated adverse events is not …