Background: Chronic ethanol consumption increases the risk of hepatic cirrhosis and
hepatocellular carcinoma (HCC). While sex differences exist in susceptibility to ethanol …

Background Chronic intake of alcohol increases the risk of gastrointestinal and hepatic
carcinogenesis. The present study was focused to investigate the incidence and mechanism …

Chronic and excessive alcohol consumption has been related to an increased risk of several
cancers, including that of the liver; however, studies in animal models have yet to …

Although alcohol effects within the liver have been extensively studied, the complex
mechanisms by which alcohol causes liver cancer are not well understood. It has been …

Chronic alcohol consumption increases the risk of hepatocellular carcinoma (HCC).
However, little is known about the potential immunological mechanisms by which ethanol …

AIM: To establish a mouse model of alcohol-driven hepatocellular carcinoma (HCC) that
develops in livers with alcoholic liver disease (ALD). METHODS: Adult C57BL/6 male mice …

Background: Alcohol is a significant risk factor for the development of hepatocellular
carcinoma (HCC). To date, no rodent model has demonstrated the formation of hepatic …

Hepatocellular carcinoma (HCC) is a significant cause of cancer-related morbidity and
mortality. Chronic, heavy ethanol consumption is a major risk for developing the worsening …

Alcohol is a well-known risk factor for hepatocellular carcinoma. Autophagy plays a dual role
in liver cancer, as it suppresses tumor initiation and promotes tumor progression …

Primary tumors of the liver represent the fifth most common type of cancer in the world and
the third leading cause of cancer-related death. Case-control studies from different countries …